Area of research
Molecular Biology · Cardiology and Cardiovascular Medicine
Research interest
Research interests include Lipid metabolism and disorders, Diabetes, Cardiovascular Risks, and Lipoproteins, Nuclear Structure and Function, and RNA Research and Splicing.
A neutralizing APOA5 monoclonal antibody reduces amounts of lipoprotein lipase in capillaries and triggers hypertriglyceridemia.
ANGPTL3/8 is an atypical unfoldase that regulates intravascular lipolysis by catalyzing unfolding of lipoprotein lipase
Dietary control of peripheral adipose storage capacity through membrane lipid remodelling
ANGPTL3/8 is an atypical unfoldase that regulates intravascular lipolysis by catalyzing unfolding of lipoprotein lipase.
T cell cholesterol transport links intestinal immune responses to dietary lipid absorption.
The accumulation of progerin underlies the loss of aortic smooth muscle cells in Hutchinson-Gilford progeria syndrome.
Distinguishing subtypes of endothelial cells in the mouse aorta.
GPIHBP1, lipoprotein lipase, and triglyceride-rich lipoproteins in capillaries of the choroid plexus and circumventricular organs
Progerin forms an abnormal meshwork and has a dominant-negative effect on the nuclear lamina
Progerin forms an abnormal meshwork and has a dominant-negative effect on the nuclear lamina.
Aster-B-dependent estradiol synthesis protects female mice from diet-induced obesity.
APOA5 deficiency causes hypertriglyceridemia by reducing amounts of lipoprotein lipase in capillaries.
Carboxyl-terminal sequences in APOA5 are important for suppressing ANGPTL3/8 activity.
T cell cholesterol transport is a metabolic checkpoint that links intestinal immune responses to dietary lipid absorption
Distinct strategies for intravascular triglyceride metabolism in hearts of mammals and lower vertebrate species
The Accumulation of Progerin Underlies the Loss of Aortic Smooth Muscle Cells in Hutchinson-Gilford Progeria Syndrome
Hepatic nonvesicular cholesterol transport is critical for systemic lipid homeostasis
Aster-dependent nonvesicular transport facilitates dietary cholesterol uptake
Aster-dependent nonvesicular transport facilitates dietary cholesterol uptake.
Hypertriglyceridemia in Apoa5–/– mice results from reduced amounts of lipoprotein lipase in the capillary lumen
The lipoprotein lipase that is shuttled into capillaries by GPIHBP1 enters the glycocalyx where it mediates lipoprotein processing.
Inverse effects of APOC2 and ANGPTL4 on the conformational dynamics of lid-anchoring structures in lipoprotein lipase.
Intracapillary LPL levels in brown adipose tissue, visualized with an antibody-based approach, are regulated by ANGPTL4 at thermoneutral temperatures.
Imaging the ANGPTL3/8-mediated regulation of lipoprotein lipase in the heart.
Revisiting the truncated lamin A produced by a commonly used strain of <i>Lmna</i> knockout mice.
CLSTN3β enforces adipocyte multilocularity to facilitate lipid utilization
Validation of the myocardial-ischaemic-injury-index machine learning algorithm to guide the diagnosis of myocardial infarction in a heterogenous population: a prespecified exploratory analysis
Electrostatic sheathing of lipoprotein lipase is essential for its movement across capillary endothelial cells
A protein of capillary endothelial cells, GPIHBP1, is crucial for plasma triglyceride metabolism.
Assessment of Oxygen Supply-Demand Imbalance and Outcomes Among Patients With Type 2 Myocardial Infarction