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Jan-Ακε Gustafsson

Karolinska Institutet · SE
Area of research
Genetics · Endocrinology, Diabetes and Metabolism
Research interest
Research interests include Estrogen and related hormone effects, Hormonal Regulation and Hypertension, Pharmacogenetics and Drug Metabolism, and Hormonal and reproductive studies.
h-index
156
citations
106,037
works
1,478
NIH funding
primary concept
email

Recent publications

Estrogen receptor β attenuates renal fibrosis by suppressing the transcriptional activity of Smad3
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 2023cited by 22position: middledoi
Myeloid LXR (Liver X Receptor) Deficiency Induces Inflammatory Gene Expression in Foamy Macrophages and Accelerates Atherosclerosis
Arteriosclerosis Thrombosis and Vascular Biology 2022cited by 73position: middledoi
Estrogen receptor β deficiency impairs gut microbiota: a possible mechanism of IBD-induced anxiety-like behavior
Microbiome 2022cited by 54position: middledoi
G protein-coupled estrogen receptor activation by bisphenol-A disrupts the protection from apoptosis conferred by the estrogen receptors ERα and ERβ in pancreatic beta cells
Environment International 2022cited by 52position: middledoi
Ahi1 regulates serotonin production by the GR/ERβ/TPH2 pathway involving sexual differences in depressive behaviors
Cell Communication and Signaling 2022cited by 45position: middledoi
Valproic acid exposure decreases neurogenic potential of outer radial glia in human brain organoids
Frontiers in Molecular Neuroscience 2022cited by 29position: middledoi
Expression of Sex Hormone Receptor and Immune Response Genes in Peripheral Blood Mononuclear Cells During the Menstrual Cycle
Frontiers in Endocrinology 2021cited by 34position: middledoi
Female mice lacking ERβ display excitatory/inhibitory synaptic imbalance to drive the pathogenesis of temporal lobe epilepsy
Theranostics 2021cited by 22position: middledoi
Stearoyl-CoA desaturase-1 impairs the reparative properties of macrophages and microglia in the brain
The Journal of Experimental Medicine 2020cited by 149position: middledoi
Intestinal estrogen receptor beta suppresses colon inflammation and tumorigenesis in both sexes
Cancer Letters 2020cited by 68position: middledoi
Bisphenol-S and Bisphenol-F alter mouse pancreatic β-cell ion channel expression and activity and insulin release through an estrogen receptor ERβ mediated pathway
Chemosphere 2020cited by 48position: middledoi
Targeting Nuclear Receptors for Cancer Therapy: Premises, Promises, and Challenges
Trends in cancer 2020cited by 33position: middledoi
VSMC-specific EP4 deletion exacerbates angiotensin II-induced aortic dissection by increasing vascular inflammation and blood pressure
Proceedings of the National Academy of Sciences 2019cited by 111position: middledoi
Differential activity of BPA, BPAF and BPC on zebrafish estrogen receptors in vitro and in vivo
Toxicology and Applied Pharmacology 2019cited by 77position: middledoi
Oestrogen receptor β mediates the actions of bisphenol-A on ion channel expression in mouse pancreatic beta cells
Diabetologia 2019cited by 61position: middledoi
Colitis‐induced colorectal cancer and intestinal epithelial estrogen receptor beta impact gut microbiota diversity
International Journal of Cancer 2018cited by 139position: middledoi
LXR Suppresses Inflammatory Gene Expression and Neutrophil Migration through cis-Repression and Cholesterol Efflux
Cell Reports 2018cited by 103position: middledoi
Pharmacological activation of estrogen receptor beta augments innate immunity to suppress cancer metastasis
Proceedings of the National Academy of Sciences 2018cited by 76position: middledoi
Role of HSD17B13 in the liver physiology and pathophysiology
Molecular and Cellular Endocrinology 2018cited by 65position: middledoi
Estrogen receptor β controls proliferation of enteric glia and differentiation of neurons in the myenteric plexus after damage
Proceedings of the National Academy of Sciences 2018cited by 50position: lastdoi
Concentrations of bile acid precursors in cerebrospinal fluid of Alzheimer's disease patients
Free Radical Biology and Medicine 2018cited by 36position: middledoi
Ablation of cytochrome P450 omega-hydroxylase 4A14 gene attenuates hepatic steatosis and fibrosis
Proceedings of the National Academy of Sciences 2017cited by 121position: middledoi
Molecular mechanisms involved in the non-monotonic effect of bisphenol-a on Ca2+ entry in mouse pancreatic β-cells
Scientific Reports 2017cited by 90position: middledoi
Genomics of sex hormone receptor signaling in hepatic sexual dimorphism
Molecular and Cellular Endocrinology 2017cited by 65position: middledoi
Estrogen receptor β, a regulator of androgen receptor signaling in the mouse ventral prostate
Proceedings of the National Academy of Sciences 2017cited by 64position: lastdoi
Defective cholesterol metabolism in amyotrophic lateral sclerosis
Journal of Lipid Research 2016cited by 163position: middledoi
Estrogen Receptor β as a Pharmaceutical Target
Trends in Pharmacological Sciences 2016cited by 119position: lastdoi
Soluble (pro)renin receptor via β-catenin enhances urine concentration capability as a target of liver X receptor
Proceedings of the National Academy of Sciences 2016cited by 100position: middledoi
On the regulatory importance of 27-hydroxycholesterol in mouse liver
The Journal of Steroid Biochemistry and Molecular Biology 2016cited by 20position: middledoi
Estrogen receptor alpha and beta in health and disease
Best Practice & Research Clinical Endocrinology & Metabolism 2015cited by 542position: lastdoi

Grants

No grants ingested yet.

Frequent collaborators

Margaret Warner · University of Houston14 papers (2013–2022)Youfei Guan · Shandong University6 papers (2013–2023)Cecilia Williams · Karolinska Institutet6 papers (2012–2018)Wen Su · University of Kentucky5 papers (2017–2023) · 5 papers (2013–2022)Xiaoyan Zhang · Dalian Ocean University5 papers (2014–2023)Per Antonson · Karolinska Institutet5 papers (2013–2022)Knut R. Steffensen · Karolinska Institutet5 papers (2012–2013) · 4 papers (2017–2022) · 4 papers (2017–2022)Bo Huang · Jiujiang University4 papers (2014–2017) · 4 papers (2013–2020)Maria Bondesson · University of Houston4 papers (2013–2019)Yunfeng Zhou · Shenzhen University3 papers (2013–2023)Johan Hartman · Karolinska University Hospital3 papers (2012–2020) · 3 papers (2013–2019) · 3 papers (2013–2020)Karin Dahlman‐Wright · Karolinska Institutet3 papers (2012–2015)Philip Jonsson · University of Houston3 papers (2012–2013)Anders Ström · University of Houston3 papers (2012–2013)