Area of research
Immunology · Infectious Diseases
Research interest
Research interests include interferon and immune responses, T-cell and B-cell Immunology, SARS-CoV-2 and COVID-19 Research, and RNA regulation and disease.
An mRNA-based broad-spectrum antiviral inspired by ISG15 deficiency protects against viral infections in vitro and in vivo
Autoimmunity in Down’s syndrome via cytokines, CD4 T cells and CD11c+ B cells
Impact of SARS-CoV-2 ORF6 and its variant polymorphisms on host responses and viral pathogenesis
A comparative study of in vitro air–liquid interface culture models of the human airway epithelium evaluating cellular heterogeneity and gene expression at single cell resolution
SARS-CoV-2 hijacks p38β/MAPK11 to promote virus replication
Nuclear RNA catabolism controls endogenous retroviruses, gene expression asymmetry, and dedifferentiation
Limited extent and consequences of pancreatic SARS-CoV-2 infection
The NF-κB Transcriptional Footprint Is Essential for SARS-CoV-2 Replication
Single-cell resolution landscape of equine peripheral blood mononuclear cells reveals diverse cell types including T-bet+ B cells
Identification of Required Host Factors for SARS-CoV-2 Infection in Human Cells
SARS-CoV-2 Orf6 hijacks Nup98 to block STAT nuclear import and antagonize interferon signaling
Complex Autoinflammatory Syndrome Unveils Fundamental Principles of JAK1 Kinase Transcriptional and Biochemical Function
Single-cell RNA sequencing of equine mesenchymal stromal cells from primary donor-matched tissue sources reveals functional heterogeneity in immune modulation and cell motility
Cyclin F Controls Cell-Cycle Transcriptional Outputs by Directing the Degradation of the Three Activator E2Fs
The ETS transcription factor ELF1 regulates a broadly antiviral program distinct from the type I interferon response
Human ADAR1 Prevents Endogenous RNA from Triggering Translational Shutdown
Inborn Errors of RNA Lariat Metabolism in Humans with Brainstem Viral Infection
Intrinsic Immunity Shapes Viral Resistance of Stem Cells
A comprehensive analysis of the effects of the deaminase AID on the transcriptome and methylome of activated B cells