Area of research
Physiology · Molecular Biology
Research interest
Research interests include Telomeres, Telomerase, and Senescence, Cancer-related Molecular Pathways, Gut microbiota and health, and Epigenetics and DNA Methylation.
Comparative analysis of senolytic drugs reveals mitochondrial determinants of efficacy and resistance.
Senescence-like cells recruit γδ T cells to drive prolonged hyposmia after SARS-CoV-2 infection in mice.
Reevaluating the senolytic activity of a GLS1 inhibitor and an anti-PD-1 antibody: toward greater reproducibility and methodological rigor.
Molecular evolution of animal aging.
Evidence that mitochondria in macrophages are destroyed by microautophagy
Refining the Feasibility of Machine-Learning-Based Diagnostic Model Utilizing Gut Microbiota Analysis for Colorectal Cancer Screening.
Selective identification of polyploid hepatocellular carcinomas with poor prognosis by artificial intelligence-based pathological image recognition.
Author Correction: RNaseH2A downregulation drives inflammatory gene expression via genomic DNA fragmentation in senescent and cancer cells.
Author Correction: Cellular senescence in white matter microglia is induced during ageing in mice and exacerbates the neuroinflammatory phenotype.
Guidelines for minimal information on cellular senescence experimentation in vivo
Crosstalk between gut microbiota and cellular senescence: a vicious cycle leading to aging gut
Multiple ageing effects on testicular/epididymal germ cells lead to decreased male fertility in mice.
Polyploidy mitigates the impact of DNA damage while simultaneously bearing its burden.
B cell senescence promotes age-related changes in oral microbiota.
Judith Campisi (1948–2024)
Third Report of the Japan Diabetes Society/Japanese Cancer Association Joint Committee on Diabetes and Cancer: Summary of the results of a questionnaire survey of oncologists and diabetologists-Secondary publication.
Cellular senescence in white matter microglia is induced during ageing in mice and exacerbates the neuroinflammatory phenotype.
Bacterial induction of B cell senescence promotes age-related changes in the gut microbiota.
An inhaled ACE2 decoy confers protection against SARS-CoV-2 infection in preclinical models.
Histological diagnosis of polyploidy discriminates an aggressive subset of hepatocellular carcinomas with poor prognosis.
Gasdermin D-mediated release of IL-33 from senescent hepatic stellate cells promotes obesity-associated hepatocellular carcinoma.
Age-associated decline of MondoA drives cellular senescence through impaired autophagy and mitochondrial homeostasis
SARS-CoV-2 infection triggers paracrine senescence and leads to a sustained senescence-associated inflammatory response.
Development and evaluation of a colorectal cancer screening method using machine learning-based gut microbiota analysis.
RNaseH2A downregulation drives inflammatory gene expression via genomic DNA fragmentation in senescent and cancer cells.
The 6th international cell senescence association conference.
Gut bacteria identified in colorectal cancer patients promote tumourigenesis via butyrate secretion.
Pericentromeric noncoding RNA changes DNA binding of CTCF and inflammatory gene expression in senescence and cancer.
A BET family protein degrader provokes senolysis by targeting NHEJ and autophagy in senescent cells.
Cellular Senescence: Defining a Path Forward