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Nicholas P. Restifo

Business Roundtable · US
Area of research
Immunology · Oncology
Research interest
Research interests include Immunotherapy and Immune Responses, CAR-T cell therapy research, Immune Cell Function and Interaction, and Cancer Immunotherapy and Biomarkers.
h-index
151
citations
96,659
works
675
NIH funding
primary concept
Medicine
email

Recent publications

LIM-domain-only 4 (LMO4) enhances CD8+ T-cell stemness and tumor rejection by boosting IL-21-STAT3 signaling
Signal Transduction and Targeted Therapy 2024cited by 17position: middledoi
Synthetic soldiers: Turning T cells into immortal warriors
The Journal of Experimental Medicine 2024cited by 4position: firstdoi
Data from Type I Cytokines Synergize with Oncogene Inhibition to Induce Tumor Growth Arrest
2023cited by 0position: lastdoi
An engineered IL-2 partial agonist promotes CD8+ T cell stemness
Nature 2021cited by 176position: middledoi
Multimodel preclinical platform predicts clinical response of melanoma to immunotherapy
Nature Medicine 2020cited by 117position: middledoi
Defining ‘T cell exhaustion’
Nature reviews. Immunology 2019cited by 1,561position: middledoi
T cell stemness and dysfunction in tumors are triggered by a common mechanism
Science 2019cited by 525position: lastdoi
Pilot Trial of Adoptive Transfer of Chimeric Antigen Receptor–transduced T Cells Targeting EGFRvIII in Patients With Glioblastoma
Journal of Immunotherapy 2019cited by 375position: middledoi
The Bone Marrow Protects and Optimizes Immunological Memory during Dietary Restriction
Cell 2019cited by 274position: middledoi
T cells genetically engineered to overcome death signaling enhance adoptive cancer immunotherapy
Journal of Clinical Investigation 2019cited by 156position: middledoi
Ribosomal Proteins Regulate MHC Class I Peptide Generation for Immunosurveillance
Molecular Cell 2019cited by 122position: middledoi
Mg2+ regulation of kinase signaling and immune function
The Journal of Experimental Medicine 2019cited by 87position: middledoi
Distinct Regulation of Th17 and Th1 Cell Differentiation by Glutaminase-Dependent Metabolism
Cell 2018cited by 688position: middledoi
Engineered T cells targeting E7 mediate regression of human papillomavirus cancers in a murine model
JCI Insight 2018cited by 163position: middledoi
Immunotherapy Bridge 2017 and Melanoma Bridge 2017: meeting abstracts
Journal of Translational Medicine 2018cited by 28position: middledoi
Identification of essential genes for cancer immunotherapy
Nature 2017cited by 890position: lastdoi
Inhibition of AKT signaling uncouples T cell differentiation from expansion for receptor-engineered adoptive immunotherapy
JCI Insight 2017cited by 218position: lastdoi
BACH2 immunodeficiency illustrates an association between super-enhancers and haploinsufficiency
Nature Immunology 2017cited by 153position: middledoi
Oxygen Sensing by T Cells Establishes an Immunologically Tolerant Metastatic Niche
Cell 2016cited by 240position: lastdoi
Constitutive LcK activity drives sensitivity differences between CD8+ memory T cell subsets
The Journal of Immunology 2016cited by 5position: middledoi
Consensus nomenclature for CD8<sup>+</sup>T cell phenotypes in cancer
OncoImmunology 2015cited by 136position: middledoi
Lineage relationship of CD8+ T cell subsets is revealed by progressive changes in the epigenetic landscape
Cellular and Molecular Immunology 2015cited by 120position: lastdoi
The kinase DYRK1A reciprocally regulates the differentiation of Th17 and regulatory T cells
eLife 2015cited by 104position: middledoi
Classification of current anticancer immunotherapies
Oncotarget 2014cited by 468position: middledoi
Type I Cytokines Synergize with Oncogene Inhibition to Induce Tumor Growth Arrest
Cancer Immunology Research 2014cited by 27position: lastdoi
T-cell receptor affinity and avidity defines antitumor response and autoimmunity in T-cell immunotherapy
Proceedings of the National Academy of Sciences 2013cited by 241position: middledoi
Uncoupling T‐cell expansion from effector differentiation in cell‐based immunotherapy
Immunological Reviews 2013cited by 117position: lastdoi

Grants

No grants ingested yet.

Frequent collaborators

Madhusudhanan Sukumar · Johnson & Johnson (United States)6 papers (2013–2019)Tori N. Yamamoto · University of California, San Francisco6 papers (2017–2021)Rigel J. Kishton · National Cancer Institute6 papers (2017–2019)Zhiya Yu · National Cancer Institute6 papers (2013–2021)Luca Gattinoni · University of Regensburg6 papers (2015–2024)Suman K. Vodnala · Lyell Immunopharma (United States)5 papers (2017–2020)Robert Eil · University of Portland5 papers (2016–2019)Christopher A. Klebanoff · Memorial Sloan Kettering Cancer Center5 papers (2015–2019)Rahul Roychoudhuri · Center for Cancer Research4 papers (2015–2019)Shashank J. Patel · Indian Agricultural Research Institute3 papers (2015–2019)Ping‐Hsien Lee · AstraZeneca (United States)3 papers (2019–2019)Douglas C. Palmer · AstraZeneca (Japan)3 papers (2015–2019)Pamela L. Schwartzberg · National Institutes of Health3 papers (2019–2019)Steven A. Rosenberg · Frederick National Laboratory for Cancer Research3 papers (2013–2019)Joseph G. Crompton · Sarcoma Oncology Center3 papers (2013–2017)Yun Ji · Center for Cancer Research2 papers (2015–2017)Devikala Gurusamy · National Heart Lung and Blood Institute2 papers (2017–2019)Glenn Merlino · National Institutes of Health2 papers (2017–2020)David Clever · The Ohio State University2 papers (2016–2017)Steven A. Feldman · Stanford University2 papers (2017–2019)