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Christine E. Bear

Hospital for Sick Children · CA
Area of research
Pulmonary and Respiratory Medicine · Molecular Biology
Research interest
Research focused on Ivacaftor and Cystic fibrosis, with related work in Mechanism of action, Exon, Action (physics). Notable publications include 'Clinical and functional efficacy of elexacaftor/tezacaftor/ivacaftor in people with cystic fibrosis carrying the N1303K mutation', 'Antisense oligonucleotide splicing modulation as a novel Cystic Fibrosis therapeutic approach for the W1282X nonsense mutation', and 'Molecular Mechanism of Action of Trimethylangelicin Derivatives as CFTR Modulators'.
h-index
citations
141
works
4
NIH funding
primary concept
email

Recent publications

Clinical and functional efficacy of elexacaftor/tezacaftor/ivacaftor in people with cystic fibrosis carrying the N1303K mutation
Journal of Cystic Fibrosis 2023cited by 53position: middledoi
Validating organoid-derived human intestinal monolayers for personalized therapy in cystic fibrosis
Life Science Alliance 2023cited by 16position: middledoi
Antisense oligonucleotide splicing modulation as a novel Cystic Fibrosis therapeutic approach for the W1282X nonsense mutation
Journal of Cystic Fibrosis 2021cited by 36position: middledoi
Molecular Mechanism of Action of Trimethylangelicin Derivatives as CFTR Modulators
Frontiers in Pharmacology 2018cited by 36position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Claire Bartlett · Hospital for Sick Children2 papers (2023–2023)Tanja Gonska · University of Toronto2 papers (2023–2023)Onofrio Laselva · Hospital for Sick Children2 papers (2018–2021)Eitan Kerem · Hadassah Medical Center2 papers (2021–2023)Theo J. Moraes · SickKids Foundation2 papers (2023–2023)Malena Cohen‐Cymberknoh · Hebrew University of Jerusalem2 papers (2021–2023)T. Gunawardena · Hospital for Sick Children2 papers (2023–2023)Batsheva Kerem · Hebrew University of Jerusalem2 papers (2021–2023)Yifat S. Oren · Hebrew University of Jerusalem1 papers (2021–2021)Ilaria Lampronti · University of Ferrara1 papers (2018–2018)Oded Breuer · Hebrew University of Jerusalem1 papers (2023–2023)R. Elgrabli · Hebrew University of Jerusalem1 papers (2021–2021)Giulio Cabrini · University of Ferrara1 papers (2018–2018)Johanna M. Rommens · SickKids Foundation1 papers (2023–2023)Christian Vaccarin · University of Padua1 papers (2018–2018)Annelotte M. Vonk · Utrecht University1 papers (2023–2023)Félix Ratjen · Hospital for Sick Children1 papers (2023–2023) · 1 papers (2023–2023)Adriana Chilin · University of Padua1 papers (2018–2018)Michael Cohen · Hebrew University of Jerusalem1 papers (2023–2023)