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Herbert Spapen

Universitair Ziekenhuis Brussel · BE
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Area of research
Epidemiology · Nephrology
Research interest
Research interests include Sepsis Diagnosis and Treatment, Acute Kidney Injury Research, Respiratory Support and Mechanisms, and Antibiotics Pharmacokinetics and Efficacy.
h-index
48
citations
10,174
works
361
NIH funding
primary concept
Medicine
email

Recent publications

Risk Factors for Intra-Abdominal Candidiasis in Intensive Care Units: Results from EUCANDICU Study
Infectious Diseases and Therapy 2022cited by 51position: middledoi
Rezafungin Versus Caspofungin in a Phase 2, Randomized, Double-blind Study for the Treatment of Candidemia and Invasive Candidiasis: The STRIVE Trial.
2021cited by 122position: contributordoi
Efficacy and safety of suvratoxumab for prevention of Staphylococcus aureus ventilator-associated pneumonia (SAATELLITE): a multicentre, randomised, double-blind, placebo-controlled, parallel-group, phase 2 pilot trial.
2021cited by 72position: contributordoi
Temporal changes in the epidemiology, management, and outcome from acute respiratory distress syndrome in European intensive care units: a comparison of two large cohorts
Critical Care 2021cited by 14position: contributordoi
Rezafungin Versus Caspofungin in a Phase 2, Randomized, Double-blind Study for the Treatment of Candidemia and Invasive Candidiasis: The STRIVE Trial
Clinical Infectious Diseases 2020cited by 152position: middledoi
Antimicrobial de-escalation in the critically ill patient and assessment of clinical cure: the DIANA study
Intensive Care Medicine 2020cited by 114position: middledoi
Nutrition in Sepsis: A Bench-to-Bedside Review.
2020cited by 63position: contributordoi
Efficacy, immunogenicity, and safety of IC43 recombinant Pseudomonas aeruginosa vaccine in mechanically ventilated intensive care patients-a randomized clinical trial.
2020cited by 56position: contributordoi
MECCIAS trial: Metabolic consequences of continuous veno-venous hemofiltration on indirect calorimetry.
2020cited by 31position: contributordoi
Energy expenditure and caloric targets during continuous renal replacement therapy under regional citrate anticoagulation. A viewpoint.
2020cited by 24position: contributordoi
The clinical relevance of oliguria in the critically ill patient: analysis of a large observational database.
2020cited by 22position: contributordoi
Dosing vitamin C in critically ill patients with special attention to renal replacement therapy: a narrative review.
2020cited by 21position: contributordoi
What is the optimal loading dose of broad-spectrum β-lactam antibiotics in septic patients? Results from pharmacokinetic simulation modelling.
2020cited by 18position: contributordoi
Acute Heart Failure as a First Presentation of Pheochromocytoma Complicated with "Inverted" Takotsubo Syndrome.
2020cited by 3position: contributordoi
An endotracheal tube providing "pressurized sealing" prevents fluid leakage in mechanically ventilated critically ill patients: a pilot study.
2020cited by 2position: contributordoi
Response to the letter of Morán et al. regarding our use of an inaccurate reference for the maximal dose of vitamin C in G6PD deficiency.
2020cited by 1position: contributordoi
Extracorporeal Carbon Dioxide Removal During Continuous Renal Replacement Therapy as Adjunctive Therapy.
2020cited by 1position: contributordoi
Correction to: Chloride content of solutions used for regional citrate anticoagulation might be responsible for blunting correction of metabolic acidosis during continuous venovenous hemofiltration.
2020cited by 0position: contributordoi
Incidence and outcome of invasive candidiasis in intensive care units (ICUs) in Europe: results of the EUCANDICU project
Critical Care 2019cited by 249position: middledoi
Effect of a Recombinant Human Soluble Thrombomodulin on Mortality in Patients With Sepsis-Associated Coagulopathy: The SCARLET Randomized Clinical Trial.
2019cited by 239position: contributordoi
Incidence and outcome of invasive candidiasis in intensive care units (ICUs) in Europe: results of the EUCANDICU project.
2019cited by 168position: contributordoi
Modification of Nutrition Therapy During Continuous Renal Replacement Therapy in Critically Ill Pediatric Patients: A Narrative Review and Recommendations.
2019cited by 30position: contributordoi
Energy expenditure of patients on ECMO: A prospective pilot study.
2019cited by 28position: contributordoi
CO<sub>2</sub> and O<sub>2</sub> removal during continuous veno-venous hemofiltration: a pilot study.
2019cited by 19position: contributordoi
Heparin-binding protein in sepsis: player! predictor! positioning?
2019cited by 14position: contributordoi
How to deal with severe acute pancreatitis in the critically ill.
2019cited by 14position: contributordoi
Hemoadsorption therapy in the critically ill: solid base but clinical haze.
2019cited by 12position: contributordoi
Unidentified cachexia patients in the oncologic setting: Cachexia UFOs do exist.
2019cited by 12position: contributordoi
Pharmacokinetics and Pharmacodynamics of Anti-infective Agents during Continuous Veno-venous Hemofiltration in Critically Ill Patients: Lessons Learned from an Ancillary Study of the IVOIRE Trial.
2019cited by 10position: contributordoi
Treatment of Ventilator-associated Pneumonia with High-dose Colistin Under Continuous Veno-venous Hemofiltration.
2019cited by 8position: contributordoi

Grants

No grants ingested yet.

Frequent collaborators

Katarzyna Kotfis · Pomeranian Medical University2 papers (2020–2021)Eric Hoste · University of Liège2 papers (2019–2021)Massimo Girardis · University of Modena and Reggio Emilia2 papers (2019–2020)Marc Leone · Université de Caen Normandie2 papers (2020–2021)Pedro Póvoa · University of Lisbon2 papers (2020–2021)Alejandro Rodríguez · Universidad Internacional del Ecuador2 papers (2020–2021)Àlex Soriano · Instituto de Salud Carlos III2 papers (2020–2021)Rupert M. Pearse · Royal London Hospital2 papers (2020–2021)Matteo Bassetti · Istituto Nazionale di Fisica Nucleare, Sezione di Genova2 papers (2019–2020)Pierre‐François Laterre · UCLouvain2 papers (2020–2021)David Brealey · University College Hospital2 papers (2020–2021)Luis Ostrosky‐Zeichner · Texas Medical Center2 papers (2020–2021)Marco Maggiorini · University Hospital of Zurich2 papers (2021–2021)José A. Vázquez · Augusta University1 papers (2020–2020)Bruno François · Hôpital Saint-Louis1 papers (2019–2019)Anita Das · Statistical Research (United States)1 papers (2020–2020)Athanasios Skoutelis · National and Kapodistrian University of Athens1 papers (2020–2020)Peter G. Pappas · University of Alabama at Birmingham1 papers (2020–2020)Taylor Sandison · Merck & Co., Inc., Rahway, NJ, USA (United States)1 papers (2020–2020)Roberto Luzzati · Ospedale Maggiore1 papers (2019–2019)
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