Area of research
Molecular Biology · Cellular and Molecular Neuroscience
Research interest
Research focused on Mitochondrion and Cell biology, with related work in Endoplasmic reticulum, MFN2, Uniporter. Notable publications include 'Mitofusin 2 ablation increases endoplasmic reticulum–mitochondria coupling', 'Enjoy the Trip: Calcium in Mitochondria Back and Forth', and 'SPLICS: a split green fluorescent protein-based contact site sensor for narrow and wide heterotypic organelle juxtaposition'.
Rescue of astrocyte activity by the calcium sensor STIM1 restores long-term synaptic plasticity in female mice modelling Alzheimer’s disease
PKA compartmentalization links cAMP signaling and autophagy
Intracellular Calcium Dysregulation by the Alzheimer’s Disease-Linked Protein Presenilin 2
Presenilin-2 and Calcium Handling: Molecules, Organelles, Cells and Brain Networks
The basics of mitochondrial cAMP signalling: Where, when, why
A Synthetic Fluorescent Mitochondria‐Targeted Sensor for Ratiometric Imaging of Calcium in Live Cells
Familial Alzheimer’s disease-linked presenilin mutants and intracellular Ca2+ handling: A single-organelle, FRET-based analysis
mCerulean3-Based Cameleon Sensor to Explore Mitochondrial Ca2+ Dynamics In Vivo
Dampened Slow Oscillation Connectivity Anticipates Amyloid Deposition in the PS2APP Mouse Model of Alzheimer’s Disease
Phosphatases control PKA-dependent functional microdomains at the outer mitochondrial membrane
Melatonin activates <scp>FIS</scp>1, <scp>DYN</scp>1, and <scp>DYN</scp>2 <i>Plasmodium falciparum</i> related‐genes for mitochondria fission: Mitoemerald‐<scp>GFP</scp> as a tool to visualize mitochondria structure
SPLICS: a split green fluorescent protein-based contact site sensor for narrow and wide heterotypic organelle juxtaposition
Guidelines on experimental methods to assess mitochondrial dysfunction in cellular models of neurodegenerative diseases
Content of mitochondrial calcium uniporter (MCU) in cardiomyocytes is regulated by microRNA-1 in physiologic and pathologic hypertrophy
Optogenetic control of mitochondrial metabolism and Ca <sup>2+</sup> signaling by mitochondria-targeted opsins
On the role of Mitofusin 2 in endoplasmic reticulum–mitochondria tethering
Enjoy the Trip: Calcium in Mitochondria Back and Forth
Presenilin 2 Modulates Endoplasmic Reticulum-Mitochondria Coupling by Tuning the Antagonistic Effect of Mitofusin 2
Sympathetic innervation controls homeostasis of neuromuscular junctions in health and disease
Exploring cells with targeted biosensors
Critical role of ATP-induced ATP release for Ca <sup>2+</sup> signaling in nonsensory cell networks of the developing cochlea
Characterization of the ER-Targeted Low Affinity Ca2+ Probe D4ER
Mitofusin 2 ablation increases endoplasmic reticulum–mitochondria coupling
Foxg1 localizes to mitochondria and coordinates cell differentiation and bioenergetics
Generation and functions of second messengers microdomains
Tumor necrosis factor-α impairs oligodendroglial differentiation through a mitochondria-dependent process
The elusive importance of being a mitochondrial Ca2+ uniporter
Aβ42 oligomers selectively disrupt neuronal calcium release
Spying on organelle Ca2+ in living cells: the mitochondrial point of view
Mitochondrial Ca2+ Uptake Induces Cyclic AMP Generation in the Matrix and Modulates Organelle ATP Levels