Area of research
Geophysics · Artificial Intelligence
Research interest
Research interests include Seismic Waves and Analysis, Seismology and Earthquake Studies, Methane Hydrates and Related Phenomena, and Geophysical Methods and Applications.
Cilia-enriched oxysterol 7β,27-DHC is required for polycystin ion channel activation
Structural bases for Na+-Cl− cotransporter inhibition by thiazide diuretic drugs and activation by kinases
Cation Chloride Cotransporter NKCC1 Operates through a Rocking-Bundle Mechanism
Structural basis for inhibition of the Cation-chloride cotransporter NKCC1 by the diuretic drug bumetanide
Structure of the human cation–chloride cotransport KCC1 in an outward-open state
Structural Pharmacology of Cation-Chloride Cotransporters
Structural mechanisms of transient receptor potential ion channels
The heteromeric PC-1/PC-2 polycystin complex is activated by the PC-1 N-terminus
Structure of the human cation–chloride cotransporter NKCC1 determined by single-particle electron cryo-microscopy
Molecular dysregulation of ciliary polycystin-2 channels caused by variants in the TOP domain
Hydrophobic pore gates regulate ion permeation in polycystic kidney disease 2 and 2L1 channels
TRPV1 structures in nanodiscs reveal mechanisms of ligand and lipid action
The Structure of the Polycystic Kidney Disease Channel PKD2 in Lipid Nanodiscs
Single particle electron cryo-microscopy of a mammalian ion channel
Structure of the TRPV1 ion channel determined by electron cryo-microscopy
TRPV1 structures in distinct conformations reveal activation mechanisms
TRPV1 Channels Are Intrinsically Heat Sensitive and Negatively Regulated by Phosphoinositide Lipids