Area of research
Genetics · Surgery
Research interest
Research focused on Inflammatory bowel disease and Ulcerative colitis, with related work in Genetics, Single-nucleotide polymorphism, ATG16L1. Notable publications include 'Host–microbe interactions have shaped the genetic architecture of inflammatory bowel disease', 'Anti-TNF antibody-induced psoriasiform skin lesions in patients with inflammatory bowel disease are characterised by interferon-γ-expressing Th1 cells and IL-17A/IL-22-expressing...', and 'IBD risk loci are enriched in multigenic regulatory modules encompassing putative causative genes'.
IBD risk loci are enriched in multigenic regulatory modules encompassing putative causative genes
A Pleiotropic Missense Variant in SLC39A8 Is Associated With Crohn’s Disease and Human Gut Microbiome Composition
A protein-truncating R179X variant in RNF186 confers protection against ulcerative colitis
Lipocalin-2 Is a Disease Activity Marker in Inflammatory Bowel Disease Regulated by IL-17A, IL-22, and TNF-α and Modulated by IL23R Genotype Status
Anti-TNF antibody-induced psoriasiform skin lesions in patients with inflammatory bowel disease are characterised by interferon-γ-expressing Th1 cells and IL-17A/IL-22-expressing Th17 cells and respond to anti-IL-12/IL-23 antibody treatment
High-density genotyping study identifies four new susceptibility loci for atopic dermatitis
Association Between Variants of PRDM1 and NDP52 and Crohn's Disease, Based on Exome Sequencing and Functional Studies
IRGM Variants and Susceptibility to Inflammatory Bowel Disease in the German Population
Host–microbe interactions have shaped the genetic architecture of inflammatory bowel disease
PTPN2 Gene Variants Are Associated with Susceptibility to Both Crohn's Disease and Ulcerative Colitis Supporting a Common Genetic Disease Background
Analysis of IL12B Gene Variants in Inflammatory Bowel Disease
PTGER4 Expression-Modulating Polymorphisms in the 5p13.1 Region Predispose to Crohn's Disease and Affect NF-κB and XBP1 Binding Sites