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Tony P. Huang

Broad Institute · US
Area of research
Molecular Biology · Epidemiology
Research interest
Research interests include CRISPR and Genetic Engineering, Advanced biosensing and bioanalysis techniques, RNA and protein synthesis mechanisms, and RNA regulation and disease.
h-index
11
citations
1,958
works
15
NIH funding
primary concept
email

Recent publications

Assigning functionality to cysteines by base editing of cancer dependency genes
Nature Chemical Biology 2023cited by 60position: middledoi
Evolution of an adenine base editor into a small, efficient cytosine base editor with low off-target activity
Nature Biotechnology 2022cited by 261position: middledoi
CRISPR-free base editors with enhanced activity and expanded targeting scope in mitochondrial and nuclear DNA
Nature Biotechnology 2022cited by 200position: middledoi
Efficient in vivo base editing via single adeno-associated viruses with size-optimized genomes encoding compact adenine base editors
Nature Biomedical Engineering 2022cited by 184position: middledoi
High-throughput continuous evolution of compact Cas9 variants targeting single-nucleotide-pyrimidine PAMs
Nature Biotechnology 2022cited by 107position: firstdoi
Publisher Correction: Efficient in vivo base editing via single adenoassociated viruses with size-optimized genomes encoding compact adenine base editors
Nature Biomedical Engineering 2022cited by 4position: middledoi
Precision genome editing using cytosine and adenine base editors in mammalian cells
Nature Protocols 2021cited by 168position: firstdoi
Publisher Correction: Precision genome editing using cytosine and adenine base editors in mammalian cells
Nature Protocols 2021cited by 7position: firstdoi
Continuous evolution of SpCas9 variants compatible with non-G PAMs
Nature Biotechnology 2020cited by 355position: middledoi
High-throughput analysis of the activities of xCas9, SpCas9-NG and SpCas9 at matched and mismatched target sequences in human cells
Nature Biomedical Engineering 2020cited by 141position: middledoi
Circularly permuted and PAM-modified Cas9 variants broaden the targeting scope of base editors
Nature Biotechnology 2019cited by 324position: firstdoi
Author Correction: Circularly permuted and PAM-modified Cas9 variants broaden the targeting scope of base editors
Nature Biotechnology 2019cited by 5position: firstdoi

Grants

Collaborative Research: Acoustic Holography Enabled Additive Manufacturing of High-resolution Multifunctional Composites
NSF2104295$200,0002021–2025PIRePORTER
Collaborative Research: High Resolution Acoustic Manipulation of Single Cells with Integrated MEMS based Phased Arrays
NSF1807601$200,0002018–2022PIRePORTER
Student Poster Symposium at ASME Society-Wide Micro and Nano Technology Forum, Houston, Texas, November 9-15, 2012
NSF1248221$26,0002012–2013PIRePORTER
EAGER: Exploring High-Resolution, Energy-Efficient, Full-Color Electronic Paper Displays (E-PADs) Driven by Rotary Molecular Motors
NSF1102206$150,0002011–2013PIRePORTER
Student Poster Symposium at ASME Society-Wide Micro and Nano Technology Forum, Denver, Colorado, November 11, 2011 - November 17, 2011
NSF1160568$40,0002011–2012PIRePORTER
Opto-Fluidic Hybrid System for Miniaturized Flow Cytometry
NSF0824183$300,0002008–2011PIRePORTER
Ultra-Small, All-Optical Plasmonic Switches Based on Light-Driven Molecular Shuttles
NSF0801922$270,0002008–2011PIRePORTER

Frequent collaborators

David R. Liu · Broad Institute12 papers (2019–2023)Aditya Raguram · Broad Institute4 papers (2022–2022)Shannon M. Miller · Dana-Farber Cancer Institute4 papers (2019–2022)Gregory A. Newby · Elon University4 papers (2020–2022)Kevin T. Zhao · Lawrence Berkeley National Laboratory3 papers (2019–2023)Samagya Banskota · Broad Institute3 papers (2022–2022)Nabil G. Seidah · University of California, Berkeley2 papers (2022–2022)Xiao Wang · Jinan Maternity And Care Hospital2 papers (2022–2022)Benjamin L. Oakes · Princeton University2 papers (2019–2019)David F. Savage · QB32 papers (2019–2019)Mandana Arbab · Broad Institute2 papers (2020–2022)Nicole M. Gaudelli · Beam Therapeutics (United States)2 papers (2019–2019)Jonathan M. Levy · Broad Institute2 papers (2022–2022)Kiran Musunuru · Williams & Associates2 papers (2022–2022)Jessie R. Davis · Broad Institute2 papers (2022–2022)Isaac P. Witte · Broad Institute2 papers (2022–2022)Christof Fellmann · Gladstone Institutes2 papers (2019–2019)Sungroh Yoon · Seoul National University1 papers (2020–2020)Holly A. Rees · Beam Therapeutics (United States)1 papers (2020–2020) · 1 papers (2020–2020)