Area of research
Aging · Endocrine and Autonomic Systems
Research interest
Research interests include Genetics, Aging, and Longevity in Model Organisms, Circadian rhythm and melatonin, Adipose Tissue and Metabolism, and Dietary Effects on Health.
Neuronal glycogen breakdown mitigates tauopathy via pentose-phosphate-pathway-mediated oxidative stress reduction
OXR1 maintains the retromer to delay brain aging under dietary restriction
Longitudinal fundus imaging and its genome-wide association analysis provide evidence for a human retinal aging clock
NIH SenNet Consortium to map senescent cells throughout the human lifespan to understand physiological health
A fly GWAS for purine metabolites identifies human FAM214 homolog medusa, which acts in a conserved manner to enhance hyperuricemia-driven pathologies by modulating purine metabolism and the inflammatory response
Skyline for Small Molecules: A Unifying Software Package for Quantitative Metabolomics
GWAS for Lifespan and Decline in Climbing Ability in Flies upon Dietary Restriction Reveal decima as a Mediator of Insulin-like Peptide Production
A conserved role of the insulin-like signaling pathway in diet-dependent uric acid pathologies in Drosophila melanogaster
The Role of Advanced Glycation End Products in Aging and Metabolic Diseases: Bridging Association and Causality
The Small GTPase RAC1/CED-10 Is Essential in Maintaining Dopaminergic Neuron Function and Survival Against α-Synuclein-Induced Toxicity
Correction to: The Small GTPase RAC1/CED-10 Is Essential in Maintaining Dopaminergic Neuron Function and Survival Against α-Synuclein-Induced Toxicity
α-Lipoic acid treatment prevents cystine urolithiasis in a mouse model of cystinuria
A Caenorhabditis elegans Model Elucidates a Conserved Role for TRPA1-Nrf Signaling in Reactive α-Dicarbonyl Detoxification
The effects of age and dietary restriction on the tissue‐specific metabolome of <i><scp>D</scp>rosophila</i>
A Drosophila Model Identifies a Critical Role for Zinc in Mineralization for Kidney Stone Disease
Iron promotes protein insolubility and aging in C. elegans
SIRT7 Represses Myc Activity to Suppress ER Stress and Prevent Fatty Liver Disease
Germline Signaling Mediates the Synergistically Prolonged Longevity Produced by Double Mutations in daf-2 and rsks-1 in C. elegans
Drosophila melanogaster as an Emerging Translational Model of Human Nephrolithiasis
Intramyocellular Fatty-Acid Metabolism Plays a Critical Role in Mediating Responses to Dietary Restriction in Drosophila melanogaster