Area of research
Physiology · Cellular and Molecular Neuroscience
Research interest
Research interests include Alzheimer's disease research and treatments, Neuroscience and Neuropharmacology Research, Neuroinflammation and Neurodegeneration Mechanisms, and Cholinesterase and Neurodegenerative Diseases.
A phase 1b randomized clinical trial of CT1812 to measure Aβ oligomer displacement in Alzheimer’s disease using an indwelling CSF catheter
Preclinical and clinical biomarker studies of CT1812: A novel approach to Alzheimer's disease modification
Exercise Training Results in Lower Amyloid Plaque Load and Greater Cognitive Function in an Intensity Dependent Manner in the Tg2576 Mouse Model of Alzheimer’s Disease
The sleep-wake cycle regulates brain interstitial fluid tau in mice and CSF tau in humans
Microglial complement receptor 3 regulates brain Aβ levels through secreted proteolytic activity
TREM2-mediated early microglial response limits diffusion and toxicity of amyloid plaques
TREM2 Lipid Sensing Sustains the Microglial Response in an Alzheimer’s Disease Model
Genetic Suppression of Transgenic APP Rescues Hypersynchronous Network Activity in a Mouse Model of Alzeimer's Disease
Levetiracetam suppresses neuronal network dysfunction and reverses synaptic and cognitive deficits in an Alzheimer’s disease model
Emergence of a seizure phenotype in aged apolipoprotein epsilon 4 targeted replacement mice