Area of research
Oncology · Genetics
Research interest
Research interests include Drug Transport and Resistance Mechanisms, Estrogen and related hormone effects, Pharmacogenetics and Drug Metabolism, and Liver Disease Diagnosis and Treatment.
Vitamin B2 enables regulation of fasting glucose availability
CAR directs T cell adaptation to bile acids in the small intestine
A human liver chimeric mouse model for non-alcoholic fatty liver disease
Mitophagy deficiency increases NLRP3 to induce brown fat dysfunction in mice
FXR-dependent Rubicon induction impairs autophagy in models of human cholestasis
Novel role of dynamin‐related‐protein 1 in dynamics of ER‐lipid droplets in adipose tissue
Vitamin D Receptor Activation in Liver Macrophages Ameliorates Hepatic Inflammation, Steatosis, and Insulin Resistance in Mice
Development of the First Low Nanomolar Liver Receptor Homolog-1 Agonist through Structure-guided Design
LRH-1 mitigates intestinal inflammatory disease by maintaining epithelial homeostasis and cell survival
miR-30a Remodels Subcutaneous Adipose Tissue Inflammation to Improve Insulin Sensitivity in Obesity
<scp>TGR</scp>5 activation induces cytoprotective changes in the heart and improves myocardial adaptability to physiologic, inotropic, and pressure‐induced stress in mice
Quantitative Real-Time Imaging of Glutathione with Subcellular Resolution
Asprosin is a centrally acting orexigenic hormone
Nutrient-sensing nuclear receptors PPARα and FXR control liver energy balance
Asprosin, a Fasting-Induced Glucogenic Protein Hormone
Circadian Homeostasis of Liver Metabolism Suppresses Hepatocarcinogenesis
Mutations in the nuclear bile acid receptor FXR cause progressive familial intrahepatic cholestasis
Vertical sleeve gastrectomy activates GPBAR‐1/TGR5 to sustain weight loss, improve fatty liver, and remit insulin resistance in mice
Bile acid excess induces cardiomyopathy and metabolic dysfunctions in the heart
Hypothalamic Vitamin D Improves Glucose Homeostasis and Reduces Weight
Lysosomal signaling molecules regulate longevity in <i>Caenorhabditis elegans</i>
Circadian Dysfunction Induces Leptin Resistance in Mice
MicroRNA-26a regulates insulin sensitivity and metabolism of glucose and lipids
Orphan Nuclear Receptor ERRα Controls Macrophage Metabolic Signaling and A20 Expression to Negatively Regulate TLR-Induced Inflammation
Nutrient-sensing nuclear receptors coordinate autophagy
Bmal1 and β-Cell Clock Are Required for Adaptation to Circadian Disruption, and Their Loss of Function Leads to Oxidative Stress-Induced β-Cell Failure in Mice
FXR-induced secretion of FGF15/19 inhibits CYP27 expression in cholangiocytes through p38 kinase pathway
BSM-PM: Searches for Beyond the Standard Model Physics with Optically Levitated Microparticle Arrays
PM: Precision Searches for Physics Beyond the Standard Model Using Optically Levitated Mcrospheres
CAREER: Searching for New Physics from a Dark Sector Using Optically Levitated Microspheres
Collaborative Research and NEON: MSB Category 2: PalEON - a PaleoEcological Observatory Network to Assess Terrestrial Ecosystem Models
RAPID Proposal: Modification of the impact of insect disturbance on carbon cycling by fire
Building a Technology Research Agenda - An Early Career Symposium
CAREER: Freeze-frame Spectroscopy, a technique for elucidation of fundamental interactions underlying nanocatalytic reactions
Building a Technology Research Agenda - An Early Career Symposium
Quantitative Network Security Analysis
Mathematical Sciences: Statistical Procedures for Errors-in-Variables Regression and Goodness of Fit
Large Sample Statistical Theory, With Emphasis on Tests of Goodness-Of-Fit