Area of research
Oncology · Immunology
Research interest
Research interests include CAR-T cell therapy research, Monoclonal and Polyclonal Antibodies Research, Immunotherapy and Immune Responses, and Biosimilars and Bioanalytical Methods.
Affinity-tuned mesothelin CAR T cells demonstrate enhanced targeting specificity and reduced off-tumor toxicity
Inducible expression of interleukin-12 augments the efficacy of affinity-tuned chimeric antigen receptors in murine solid tumor models
Bispecific CAR T Cells against EpCAM and Inducible ICAM-1 Overcome Antigen Heterogeneity and Generate Superior Antitumor Responses
Chimeric Antigen Receptor T Cell Therapy Targeting ICAM-1 in Gastric Cancer
PD1 Blockade Enhances ICAM1-Directed CAR T Therapeutic Efficacy in Advanced Thyroid Cancer
Manufacturing and preclinical validation of CAR T cells targeting ICAM-1 for advanced thyroid cancer therapy
Abstract 2322: ICAM-1 targeting CAR T cell therapy for triple negative breast cancer
Micromolar affinity CAR T cells to ICAM-1 achieves rapid tumor elimination while avoiding systemic toxicity
CAR T Therapy Targeting ICAM-1 Eliminates Advanced Human Thyroid Tumors
Longitudinal PET imaging demonstrates biphasic CAR T cell responses in survivors