Area of research
Pulmonary and Respiratory Medicine · Neurology
Research interest
Research interests include Sarcoma Diagnosis and Treatment, Neuroblastoma Research and Treatments, Cancer, Hypoxia, and Metabolism, and Cancer Genomics and Diagnostics.
Targeting metastasis in paediatric bone sarcomas
Genomic and phenotypic stability of fusion-driven pediatric sarcoma cell lines
Patient-derived tumoroids from CIC::DUX4 rearranged sarcoma identify MCL1 as a therapeutic target
Recurrent and Refractory Ewing Sarcoma Phase I/II Trials: Current Perspective From the Euro-Ewing Consortium
Advancing Preclinical Biology for Ewing Sarcoma: An International Effort
Functional Classification of Fusion Proteins in Sarcoma
Reversible transitions between noradrenergic and mesenchymal tumor identities define cell plasticity in neuroblastoma
A biobank of pediatric patient-derived-xenograft models in cancer precision medicine trial MAPPYACTS for relapsed and refractory tumors
VGLL2-NCOA2 leverages developmental programs for pediatric sarcomagenesis
Targeted long-read sequencing of the Ewing sarcoma 6p25.1 susceptibility locus identifies germline-somatic interactions with EWSR1-FLI1 binding
Abstract 234: ITCC-P4: Genomic profiling and analyses of pediatric patient tumor and patient-derived xenograft (PDX) models for high throughput <i>in vivo</i> testing
Genomic and phenotypic stability of fusion-driven pediatric Ewing sarcoma cell lines
Systematic multi-omics cell line profiling uncovers principles of Ewing sarcoma fusion oncogene-mediated gene regulation
An international working group consensus report for the prioritization of molecular biomarkers for Ewing sarcoma
Oncogenic chimeric transcription factors drive tumor-specific transcription, processing, and translation of silent genomic regions
Molecular Characterization of Circulating Tumor DNA in Pediatric Rhabdomyosarcoma: A Feasibility Study
INSP-15. ITCC-P4: A sustainable platform of molecularly well-characterized PDX models of pediatric cancers for high throughput<i>in vivo</i> testing
STAG2 mutations alter CTCF-anchored loop extrusion, reduce cis-regulatory interactions and EWSR1-FLI1 activity in Ewing sarcoma
Unraveling Ewing Sarcoma Tumorigenesis Originating from Patient-Derived Mesenchymal Stem Cells
ERG transcription factors have a splicing regulatory function involving RBFOX2 that is altered in the EWS-FLI1 oncogenic fusion
Systematic multi-omics cell line profiling uncovers principles of Ewing sarcoma fusion oncogene-mediated gene regulation
Locoregionally administered B7-H3-targeted CAR T cells for treatment of atypical teratoid/rhabdoid tumors
Transcriptional Programs Define Intratumoral Heterogeneity of Ewing Sarcoma at Single-Cell Resolution
High Specificity of BCL11B and GLG1 for EWSR1-FLI1 and EWSR1-ERG Positive Ewing Sarcoma
Low-frequency variation near common germline susceptibility loci are associated with risk of Ewing sarcoma
Cooperation of cancer drivers with regulatory germline variants shapes clinical outcomes
Genome-wide association study identifies multiple new loci associated with Ewing sarcoma susceptibility
Cooperation of dominant oncogenes with regulatory germline variants shapes clinical outcomes in childhood cancer