Area of research
Cell Biology · Molecular Biology
Research interest
Research focused on Kinetochore and BUB1, with related work in Spindle checkpoint, Cell biology, Mitosis. Notable publications include 'Oral Mucosal Organoids as a Potential Platform for Personalized Cancer Therapy', 'Evolutionary dynamics of the kinetochore network in eukaryotes as revealed by comparative genomics', and 'Negative feedback at kinetochores underlies a responsive spindle checkpoint signal'.
Reconstructing the last common ancestor of all eukaryotes
Desmosomal protein degradation as an underlying cause of arrhythmogenic cardiomyopathy
Microtubule nucleation from the fibrous corona by LIC1-pericentrin promotes chromosome congression
Lymphatic Invasion of Plakoglobin-Dependent Tumor Cell Clusters Drives Formation of Polyclonal Lung Metastases in Colon Cancer
Nuclear chromosome locations dictate segregation error frequencies
Molecular characterization of colorectal cancer related peritoneal metastatic disease
Reconstructing single-cell karyotype alterations in colorectal cancer identifies punctuated and gradual diversification patterns
Chromosomal instability by mutations in the novel minor spliceosome component CENATAC
BCL-XL is crucial for progression through the adenoma-to-carcinoma sequence of colorectal cancer
Compromised MPS1 Activity Induces Multipolar Spindle Formation in Oocytes From Aged Mares: Establishing the Horse as a Natural Animal Model to Study Age-Induced Oocyte Meiotic Spindle Instability
Evolutionary Dynamics of the Spindle Assembly Checkpoint in Eukaryotes
Oral Mucosal Organoids as a Potential Platform for Personalized Cancer Therapy
Human chromosome‐specific aneuploidy is influenced by DNA‐dependent centromeric features
Mosaic origin of the eukaryotic kinetochore
Organoids from colorectal peritoneal metastases as a platform for improving hyperthermic intraperitoneal chemotherapy
The molecular basis of monopolin recruitment to the kinetochore
Dynamic kinetochore size regulation promotes microtubule capture and chromosome biorientation in mitosis
Evolutionary dynamics of the kinetochore network in eukaryotes as revealed by comparative genomics
Unique Phylogenetic Distributions of the Ska and Dam1 Complexes Support Functional Analogy and Suggest Multiple Parallel Displacements of Ska by Dam1
Phylogenomics-guided discovery of a novel conserved cassette of short linear motifs in BubR1 essential for the spindle checkpoint
A molecular basis for the differential roles of Bub1 and BubR1 in the spindle assembly checkpoint
Plk1 and Mps1 Cooperatively Regulate the Spindle Assembly Checkpoint in Human Cells
Dissecting the roles of human BUB1 in the spindle assembly checkpoint
Widespread Recurrent Patterns of Rapid Repeat Evolution in the Kinetochore Scaffold KNL1
Negative feedback at kinetochores underlies a responsive spindle checkpoint signal
Assessing Kinetics from Fixed Cells Reveals Activation of the Mitotic Entry Network at the S/G2 Transition
Conditional targeting of MAD1 to kinetochores is sufficient to reactivate the spindle assembly checkpoint in metaphase
Arrayed BUB recruitment modules in the kinetochore scaffold KNL1 promote accurate chromosome segregation
A TPR domain–containing N-terminal module of MPS1 is required for its kinetochore localization by Aurora B
Universal Quantitative Kinase Assay Based on Diagonal SCX Chromatography and Stable Isotope Dimethyl Labeling Provides High-definition Kinase Consensus Motifs for PKA and Human Mps1