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Allan Zajac

University of Alabama at Birmingham · US
Area of research
Immunology · Oncology
Research interest
Research focused on CD8 and Effector, with related work in Immunology, FOXP3, Germinal center. Notable publications include 'CD4+ T Cell Help Is Required for the Formation of a Cytolytic CD8+ T Cell Subset that Protects against Chronic Infection and Cancer', 'T cell exhaustion during persistent viral infections', and 'Dynamic regulation of T follicular regulatory cell responses by interleukin 2 during influenza infection'.
h-index
citations
2,321
works
22
NIH funding
primary concept
email

Recent publications

Gfi1 controls the formation of effector-like CD8+ T cells during chronic infection and cancer
Nature Communications 2025cited by 5position: middledoi
Tfh-cell-derived interleukin 21 sustains effector CD8+ T cell responses during chronic viral infection
Immunity 2022cited by 138position: middledoi
Intrinsic IL-2 production by effector CD8 T cells affects IL-2 signaling and promotes fate decisions, stemness, and protection
Science Immunology 2022cited by 70position: lastdoi
IL-10–producing Tfh cells accumulate with age and link inflammation with age-related immune suppression
Science Advances 2020cited by 119position: middledoi
CD4+ T Cell Help Is Required for the Formation of a Cytolytic CD8+ T Cell Subset that Protects against Chronic Infection and Cancer
Immunity 2019cited by 645position: middledoi
Immune Exhaustion: Past Lessons and New Insights from Lymphocytic Choriomeningitis Virus
Viruses 2019cited by 44position: lastdoi
IL-21 Controls ILC3 Cytokine Production and Promotes a Protective Phenotype in a Mouse Model of Colitis
ImmunoHorizons 2019cited by 16position: middledoi
Dynamic regulation of T follicular regulatory cell responses by interleukin 2 during influenza infection
Nature Immunology 2017cited by 225position: middledoi
IL-21 and T Cell Differentiation: Consider the Context
Trends in Immunology 2016cited by 149position: lastdoi
A Context-Dependent Role for IL-21 in Modulating the Differentiation, Distribution, and Abundance of Effector and Memory CD8 T Cell Subsets
The Journal of Immunology 2016cited by 48position: lastdoi
IL-10 Regulates Memory T Cell Development and the Balance between Th1 and Follicular Th Cell Responses during an Acute Viral Infection
The Journal of Immunology 2016cited by 45position: lastdoi
T cell exhaustion during persistent viral infections
Virology 2015cited by 324position: lastdoi
Interleukin‐21 Promotes Germinal Center Reaction by Skewing the Follicular Regulatory T Cell to Follicular Helper T Cell Balance in Autoimmune BXD2 Mice
Arthritis & Rheumatology 2014cited by 106position: middledoi
Effects of atorvastatin and pravastatin on immune activation and T-cell function in antiretroviral therapy-suppressed HIV-1-infected patients
AIDS 2014cited by 26position: middledoi
Tissue-resident T cells lose their S1P1 exit visas
Cellular and Molecular Immunology 2014cited by 16position: firstdoi
Cytotoxic T Lymphocytes
2014cited by 6position: lastdoi
IL-17RA Is Essential for Optimal Localization of Follicular Th Cells in the Germinal Center Light Zone To Promote Autoantibody-Producing B Cells
The Journal of Immunology 2013cited by 86position: middledoi
ICAM-1–dependent tuning of memory CD8 T-cell responses following acute infection
Proceedings of the National Academy of Sciences 2013cited by 47position: lastdoi
Virus-specific CD4 and CD8 T cell responses in the absence of Th1-associated transcription factors
Journal of Leukocyte Biology 2013cited by 20position: middledoi
IL-21 optimizes T cell and humoral responses in the central nervous system during viral encephalitis
Journal of Neuroimmunology 2013cited by 19position: middledoi
Temporal Requirements for B Cells in the Establishment of CD4 T Cell Memory
The Journal of Immunology 2013cited by 16position: middledoi
Anti-viral CD8 T cells and the cytokines that they love
Virology 2012cited by 151position: lastdoi

Grants

No grants ingested yet.

Frequent collaborators

Jennifer T Ingram · University of Alabama at Birmingham6 papers (2013–2025)Laurie E. Harrington · University of Alabama at Birmingham6 papers (2013–2022)Shannon M. Kahan · University of Alabama at Birmingham6 papers (2012–2022)Maureen A. Cox · University of Alabama at Birmingham4 papers (2012–2016)Yuan Tian · Ministry of Education3 papers (2016–2016)Rakesh K. Bakshi · University of Alabama at Birmingham3 papers (2014–2022)Sarah B. Mollo · University of Alabama at Birmingham3 papers (2013–2016)Hui‐Chen Hsu · University of Alabama at Birmingham2 papers (2013–2014)Bao Luo · University of Alabama at Birmingham2 papers (2013–2014)Yanna Ding · University of Alabama at Birmingham2 papers (2013–2014)John D. Mountz · University of Alabama at Birmingham2 papers (2013–2014)Ryan Zander · University of Iowa2 papers (2019–2022)Weiguo Cui · Northwestern University2 papers (2019–2022)PingAr Yang · University of Alabama at Birmingham2 papers (2013–2014)Robert Burns · Versiti Blood Center of Wisconsin1 papers (2022–2022)Nikhil S. Joshi · JSS Science and Technology University1 papers (2022–2022)Shikan Zheng · Medical College of Wisconsin1 papers (2022–2022)Jun Li · St. Jude Children's Research Hospital1 papers (2014–2014)Jun Li · Qinghai University1 papers (2013–2013)Gang Xin · Medical College of Wisconsin1 papers (2019–2019)