Area of research
Molecular Biology · Oncology
Research interest
Research interests include Cell death mechanisms and regulation, CAR-T cell therapy research, Neuroblastoma Research and Treatments, and Acute Lymphoblastic Leukemia research.
IRF2BP2::JAK2 Defines a Novel Kinase-Activating Fusion in Pediatric T-Cell Acute Lymphoblastic Leukemia.
Precision-guided therapy in H3K27-altered diffuse midline glioma.
Comprehensive Multiplatform Tyrosine Kinase Profiling Reveals Novel Actionable FGFR Aberrations across Sarcomas Affecting the Young.
Integrated Germline and Somatic Molecular Profiling to Detect Cancer Predisposition Has a High Clinical Impact in Poor-Prognosis Pediatric Cancer.
PDGFRA in paediatric high-grade glioma - target or distraction?
A novel TRKB-activating internal tandem duplication characterizes a new mechanism of receptor tyrosine kinase activation
Systematic silencing of oncogenic fusion transcripts with ultra-precise CRISPR-Cas13b
A novel TRKB-activating internal tandem duplication characterizes a new mechanism of receptor tyrosine kinase activation.
Expanding the utility of transcriptome analysis for mutation detection in high-risk childhood precision oncology
Figure S6 from Distinct Assemblies of Heterodimeric Cytokine Receptors Govern Stemness Programs in Leukemia
Data from Distinct Assemblies of Heterodimeric Cytokine Receptors Govern Stemness Programs in Leukemia
Figure S7 from Distinct Assemblies of Heterodimeric Cytokine Receptors Govern Stemness Programs in Leukemia
Supplementary Table S1 from Distinct Assemblies of Heterodimeric Cytokine Receptors Govern Stemness Programs in Leukemia
Figure S4 from Distinct Assemblies of Heterodimeric Cytokine Receptors Govern Stemness Programs in Leukemia
Supplementary Table S2 from Distinct Assemblies of Heterodimeric Cytokine Receptors Govern Stemness Programs in Leukemia
Figure S3 from Distinct Assemblies of Heterodimeric Cytokine Receptors Govern Stemness Programs in Leukemia
Figure S1 from Distinct Assemblies of Heterodimeric Cytokine Receptors Govern Stemness Programs in Leukemia
Single-cell RNA-sequencing of cerebral spinal fluid identifies circulating tumour cells in children with brain cancer
Figure S5 from Distinct Assemblies of Heterodimeric Cytokine Receptors Govern Stemness Programs in Leukemia
CBL mutations in pediatric solid and CNS tumors are a marker of receptor tyrosine kinase activation and a potential therapeutic target
Figure S2 from Distinct Assemblies of Heterodimeric Cytokine Receptors Govern Stemness Programs in Leukemia
Precision-guided treatment in high-risk pediatric cancers.
Single-base tiled screen unveils design principles of PspCas13b for potent and off-target-free RNA silencing.
Principles of CRISPR-Cas13 mismatch intolerance enable selective silencing of point-mutated oncogenic RNA with single-base precision.
A novel MYB::PAIP1 oncogenic fusion in pediatric blastic plasmacytoid dendritic cell neoplasm (BPDCN) is dependent on BCL2 expression and is sensitive to venetoclax.
Functional precision medicine for pediatric cancers.
Novel paediatric case of a spinal high-grade astrocytoma with piloid features in a patient with Noonan Syndrome.
Author Correction: Functional precision medicine for pediatric cancers.
Integrated germline and somatic molecular profiling to detect cancer predisposition has a high clinical impact in poor-prognosis paediatric cancer
Patient Experience of Complex Genomic Sequencing Exploring Patient Preference, Barriers, and Enablers for Delivery.