Area of research
Molecular Biology · Cellular and Molecular Neuroscience
Research interest
Research interests include Nicotinic Acetylcholine Receptors Study, Receptor Mechanisms and Signaling, Neurotransmitter Receptor Influence on Behavior, and Ion channel regulation and function.
Selective Inhibition of Rat α7 Nicotinic Acetylcholine Receptors by LvID, a Newly Characterized α4/7-Conotoxin from <i>Conus lividus</i>
An N-Terminally Elongated Peptide From Conus rolani Defines a New Class of Ribbon α-Conotoxins Targeting Muscle nAChRs.
Shape-Shifting Conotoxins Reveal Divergent Pore-Targeting Mechanisms in Nicotinic Receptors
Conotoxins Targeting Voltage-Gated Sodium Ion Channels
Conotoxins Targeting Voltage-Gated Sodium Ion Channels.
αO-Conotoxin GeXIVA[1,2] Reduced Neuropathic Pain and Changed Gene Expression in Chronic Oxaliplatin-Induced Neuropathy Mice Model
Computational Design of α-Conotoxins to Target Specific Nicotinic Acetylcholine Receptor Subtypes.
Analogs of α-conotoxin PnIC selectively inhibit α7β2- over α7-only subtype nicotinic acetylcholine receptors via a novel allosteric mechanism.
Using Constellation Pharmacology to Characterize a Novel α-Conotoxin from <i>Conus ateralbus</i>.
Nicotinic acetylcholine receptors: Therapeutic targets for novel ligands to treat pain and inflammation
Role of α6-Nicotinic Receptors in Alcohol-Induced GABAergic Synaptic Transmission and Plasticity to Cholinergic Interneurons in the Nucleus Accumbens
DM506 (3-Methyl-1,2,3,4,5,6-hexahydroazepino[4,5-<i>b</i>]indole fumarate), a Novel Derivative of Ibogamine, Inhibits α7 and α9α10 Nicotinic Acetylcholine Receptors by Different Allosteric Mechanisms
Comparison of the Anti-inflammatory Properties of Two Nicotinic Acetylcholine Receptor Ligands, Phosphocholine and pCF3-diEPP
Alkaloid ligands enable function of homomeric human α10 nicotinic acetylcholine receptors
RgIA4 Prevention of Acute Oxaliplatin-Induced Cold Allodynia Requires α9-Containing Nicotinic Acetylcholine Receptors and CD3+ T-Cells
Rapid multi-directed cholinergic transmission in the central nervous system
Selective Penicillamine Substitution Enables Development of a Potent Analgesic Peptide that Acts through a Non-Opioid-Based Mechanism
Discovery of Methylene Thioacetal-Incorporated α-RgIA Analogues as Potent and Stable Antagonists of the Human α9α10 Nicotinic Acetylcholine Receptor for the Treatment of Neuropathic Pain
Computational and Functional Mapping of Human and Rat α6β4 Nicotinic Acetylcholine Receptors Reveals Species-Specific Ligand-Binding Motifs
Cy3-RgIA-5727 Labels and Inhibits α9-Containing nAChRs of Cochlear Hair Cells
Curses or Cures: A Review of the Numerous Benefits Versus the Biosecurity Concerns of Conotoxin Research
The α9α10 nicotinic acetylcholine receptors antagonist α-conotoxin RgIA reverses colitis signs in murine dextran sodium sulfate model
Behavioral and Molecular Basis of Cholinergic Modulation of Pain: Focus on Nicotinic Acetylcholine Receptors
Rapid ‘multi-directed’ cholinergic transmission at central synapses
Full activation of an α7-α3β4 nicotinic receptor complex avoids receptor desensitization in human chromaffin cells
Overexpression of P2X3 and P2X7 Receptors and TRPV1 Channels in Adrenomedullary Chromaffin Cells in a Rat Model of Neuropathic Pain
Conopeptides [V11L;V16D]ArIB and RgIA4: Powerful Tools for the Identification of Novel Nicotinic Acetylcholine Receptors in Monocytes
RgIA4 Accelerates Recovery from Paclitaxel-Induced Neuropathic Pain in Rats
SLPI Inhibits ATP-Mediated Maturation of IL-1β in Human Monocytic Leukocytes: A Novel Function of an Old Player
Photoactivatable drugs for nicotinic optopharmacology