Area of research
Oncology · Genetics
Research interest
Research interests include CAR-T cell therapy research, Glioma Diagnosis and Treatment, Immunotherapy and Immune Responses, and Single-cell and spatial transcriptomics.
Tumour-wide RNA splicing aberrations generate actionable public neoantigens
Glioma-neuronal circuit remodeling induces regional immunosuppression
Ultrasound frequency-controlled microbubble dynamics in brain vessels regulate the enrichment of inflammatory pathways in the blood-brain barrier
Enhancing CAR-T cell metabolism to overcome hypoxic conditions in the brain tumor microenvironment
DDEL-10. MICROBUBBLE-ENHANCED FOCUSED ULTRASOUND REGULATES THE ENRICHMENT OF INFLAMMATORY PATHWAYS IN THE BLOOD-BRAIN BARRIER AND IMPROVES CAR T CELL ACCUMULATION IN GLIOMAS
Efficacy of cancer-specific anti-podoplanin CAR-T cells and oncolytic herpes virus G47Δ combination therapy against glioblastoma