Area of research
Molecular Biology · Immunology
Research interest
Research interests include Trypanosoma species research and implications, RNA regulation and disease, T-cell and B-cell Immunology, and Immune Cell Function and Interaction.
DGAT1 mediates sex-specific CD8+ T cell antitumour responses
Serine enrichment in tumors promotes regulatory T cell accumulation through sphinganine-mediated regulation of c-Fos
APOBEC2 safeguards skeletal muscle cell fate through binding chromatin and regulating transcription of non-muscle genes during myoblast differentiation
The fentanyl-specific antibody FenAb024 can shield against carfentanil effects
ADAR1-mediated RNA editing promotes B cell lymphomagenesis
A trypanosome-derived immunotherapeutics platform elicits potent high-affinity antibodies, negating the effects of the synthetic opioid fentanyl
Immunodominant surface epitopes power immune evasion in the African trypanosome
A structural classification of the variant surface glycoproteins of the African trypanosome
ADAR RNA editing on antisense RNAs results in apparent U-to-C base changes on overlapping sense transcripts
Structural similarities between the metacyclic and bloodstream form variant surface glycoproteins of the African trypanosome
A Structural Classification of the Variant Surface Glycoproteins of the African Trypanosome
Employing RNA editing to engineer personalized tumor-specific neoantigens (editopes)
Functions and consequences of AID/APOBEC-mediated DNA and RNA deamination
Rapid, adaptable and sensitive Cas13-based COVID-19 diagnostics using ADESSO
RNA Editing Alterations Define Disease Manifestations in the Progression of Experimental Autoimmune Encephalomyelitis (EAE)
Immunization with Genetically Modified Trypanosomes Provides Protection against Transmissible Spongiform Encephalopathies
An Epitope-Focused Trypanosome-Derived Vaccine Platform Elicits High-Affinity Antibodies and Immunity Against Fentanyl Effects
Acute expression of human APOBEC3B in mice causes lethality associated with RNA editing
SARS-CoV-2 variant evolution in the United States: High accumulation of viral mutations over time likely through serial Founder Events and mutational bursts
Structure of trypanosome coat protein VSGsur and function in suramin resistance
Harnessing self-labeling enzymes for selective and concurrent A-to-I and C-to-U RNA base editing
Nanobody-mediated macromolecular crowding induces membrane fission and remodeling in the African trypanosome
SARS-CoV-2 variant evolution in the United States: High accumulation of viral mutations over time likely through serial Founder Events and mutational bursts
Immunodominant surface epitopes power immune evasion in the African trypanosome
ADESSO: a rapid, adaptable and sensitive Cas13-based COVID-19 diagnostic platform
Nanobody Mediated Macromolecular Crowding Induces Membrane Fission and Remodeling in the African Trypanosome
CYTIDINE DEAMINASES SHAPE THE GENOME OF GERMINAL CENTER B CELL DERIVED LYMPHOMA
C-to-U RNA Editing: From Computational Detection to Experimental Validation
ADAR1 can drive Multiple Myeloma progression by acting both as an RNA editor of specific transcripts and as a DNA mutator of their cognate genes
APOBEC2 is a Transcriptional Repressor required for proper Myoblast Differentiation