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Suzie J. Scales

Amgen (United States) · US
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Area of research
Radiology, Nuclear Medicine and Imaging · Oncology
Research interest
Research focused on Cell biology and Antibody, with related work in Podocyte, Internalization, Proteasome. Notable publications include 'Systematic evaluation of antibody-mediated siRNA delivery using an industrial platform of THIOMAB–siRNA conjugates', 'Targeted degradation via direct 26S proteasome recruitment', and 'The Orphan G Protein-coupled Receptor Gpr175 (Tpra40) Enhances Hedgehog Signaling by Modulating cAMP Levels'.
h-index
citations
594
works
9
NIH funding
primary concept
email

Recent publications

Apolipoprotein L1 (APOL1) renal risk variant-mediated podocyte cytotoxicity depends on African haplotype and surface expression
Scientific Reports 2024cited by 19position: lastdoi
Targeted degradation via direct 26S proteasome recruitment
Nature Chemical Biology 2022cited by 108position: middledoi
Structures of the ApoL1 and ApoL2 N-terminal domains reveal a non-classical four-helix bundle motif
Communications Biology 2021cited by 17position: middledoi
Apolipoprotein L1-Specific Antibodies Detect Endogenous APOL1 inside the Endoplasmic Reticulum and on the Plasma Membrane of Podocytes
Journal of the American Society of Nephrology 2020cited by 53position: firstdoi
Tetravalent biepitopic targeting enables intrinsic antibody agonism of tumor necrosis factor receptor superfamily members.
PubMed 2020cited by 30position: middledoi
The Orphan G Protein-coupled Receptor Gpr175 (Tpra40) Enhances Hedgehog Signaling by Modulating cAMP Levels
Journal of Biological Chemistry 2015cited by 83position: lastdoi
Systematic evaluation of antibody-mediated siRNA delivery using an industrial platform of THIOMAB–siRNA conjugates
Nucleic Acids Research 2014cited by 204position: middledoi
An Antimesothelin-Monomethyl Auristatin E Conjugate with Potent Antitumor Activity in Ovarian, Pancreatic, and Mesothelioma Models
Molecular Cancer Therapeutics 2014cited by 67position: firstdoi
DropArray™, a Wall‐Less 96‐Well Plate for Uptake and Immunofluorescence Microscopy, Confirms <scp>CD22</scp> Recycles
Traffic 2013cited by 13position: lastdoi

Grants

No grants ingested yet.

Frequent collaborators

· 3 papers (2020–2024)Xiaohui Wen · Beijing Chao-Yang Hospital2 papers (2014–2015)Gladys S. Ingle · Gene Therapy Laboratory2 papers (2013–2014)Ann M. De Mazière · Utrecht University2 papers (2020–2024)Judith Klumperman · Utrecht University2 papers (2020–2024)Wayne J. Fairbrother · Amgen (United States)2 papers (2021–2022) · 2 papers (2020–2021) · 2 papers (2020–2021)Francesca Oltrabella · University of California, San Francisco2 papers (2020–2021)Josefa Chuh · Amgen (United States)1 papers (2014–2014) · 1 papers (2014–2014)Tianbo Li · Jiangsu University1 papers (2024–2024) · 1 papers (2022–2022) · 1 papers (2020–2020)Linda Rangell · Sunesis (United States)1 papers (2014–2014) · 1 papers (2020–2020)Yin Zhang · Zhengzhou University1 papers (2014–2014)Yingnan Zhang · Georgia Institute of Technology1 papers (2022–2022)Chen Gu · Massachusetts Institute of Technology1 papers (2020–2020) · 1 papers (2020–2020)
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