Area of research
Cell Biology · Pulmonary and Respiratory Medicine
Research interest
Research interests include Hippo pathway signaling and YAP/TAZ, Occupational and environmental lung diseases, Cancer Research and Treatments, and Cancer Immunotherapy and Biomarkers.
Steatotic liver disease induces YAP/TAZ-driven cell competition that can suppress tumor initiation
Single-cell spatial multi-omics and deep learning dissect enhancer-driven gene regulatory networks in liver zonation
A Novel Irreversible TEAD Inhibitor, SWTX-143, Blocks Hippo Pathway Transcriptional Output and Causes Tumor Regression in Preclinical Mesothelioma Models
Regeneration Defects in Yap and Taz Mutant Mouse Livers Are Caused by Bile Duct Disruption and Cholestasis
Peritumoral activation of the Hippo pathway effectors YAP and TAZ suppresses liver cancer in mice