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Luke Esposito

Allen Institute for Brain Science · US
Area of research
Molecular Biology · Physiology
Research interest
Research interests include Single-cell and spatial transcriptomics, Alzheimer's disease research and treatments, Neuroinflammation and Neurodegeneration Mechanisms, and Neural dynamics and brain function.
h-index
32
citations
7,815
works
56
NIH funding
primary concept
Biology
email

Recent publications

Brain-wide cell-type-specific transcriptomic signatures of healthy ageing in mice
Nature 2025cited by 102position: middledoi
Integrated Classification of Cortical Cells and Quantitative Projectomic Mapping Unveil Organizational Principles of Brain-Wide Connectomes at Single Cell Level
bioRxiv (Cold Spring Harbor Laboratory) 2025cited by 0position: middledoi
Integrated multimodal cell atlas of Alzheimer’s disease
Nature Neuroscience 2024cited by 234position: middledoi
A high-resolution transcriptomic and spatial atlas of cell types in the whole mouse brain
Nature 2023cited by 1,000position: middledoi
A high-resolution transcriptomic and spatial atlas of cell types in the whole mouse brain
bioRxiv (Cold Spring Harbor Laboratory) 2023cited by 138position: middledoi
Signature morphoelectric properties of diverse GABAergic interneurons in the human neocortex
Science 2023cited by 118position: middledoi
Morphoelectric and transcriptomic divergence of the layer 1 interneuron repertoire in human versus mouse neocortex
Science 2023cited by 80position: middledoi
Integrated multimodal cell atlas of Alzheimer’s disease
Research Square 2023cited by 63position: middledoi
Integrated multimodal cell atlas of Alzheimer’s disease
bioRxiv (Cold Spring Harbor Laboratory) 2023cited by 40position: middledoi
Connecting single-cell transcriptomes to projectomes in mouse visual cortex
bioRxiv (Cold Spring Harbor Laboratory) 2023cited by 15position: middledoi
Cell-type specific molecular signatures of aging revealed in a brain-wide transcriptomic cell-type atlas
bioRxiv (Cold Spring Harbor Laboratory) 2023cited by 9position: middledoi
Local connectivity and synaptic dynamics in mouse and human neocortex
Science 2022cited by 379position: middledoi
Morpho-electric and transcriptomic divergence of the layer 1 interneuron repertoire in human versus mouse neocortex
bioRxiv (Cold Spring Harbor Laboratory) 2022cited by 14position: middledoi
Survey of spiking in the mouse visual system reveals functional hierarchy
Nature 2021cited by 645position: middledoi
Morphological diversity of single neurons in molecularly defined cell types
Nature 2021cited by 418position: middledoi
Enhancer viruses for combinatorial cell-subclass-specific labeling
Neuron 2021cited by 204position: middledoi
Integrated Morphoelectric and Transcriptomic Classification of Cortical GABAergic Cells
Cell 2020cited by 552position: middledoi
Toward an integrated classification of neuronal cell types: morphoelectric and transcriptomic characterization of individual GABAergic cortical neurons
bioRxiv (Cold Spring Harbor Laboratory) 2020cited by 43position: middledoi
Brain-wide single neuron reconstruction reveals morphological diversity in molecularly defined striatal, thalamic, cortical and claustral neuron types
Research Square 2020cited by 19position: middledoi
Toward an Integrated Classification of Cell Types: Morphoelectric and Transcriptomic Characterization of Individual GABAergic Cortical Neurons
SSRN Electronic Journal 2020cited by 3position: middledoi
A survey of spiking activity reveals a functional hierarchy of mouse corticothalamic visual areas
bioRxiv (Cold Spring Harbor Laboratory) 2019cited by 69position: middledoi
Brain-wide single neuron reconstruction reveals morphological diversity in molecularly defined striatal, thalamic, cortical and claustral neuron types
bioRxiv (Cold Spring Harbor Laboratory) 2019cited by 48position: middledoi
Enhancer viruses and a transgenic platform for combinatorial cell subclass-specific labeling
bioRxiv (Cold Spring Harbor Laboratory) 2019cited by 31position: middledoi
Complete Whole-Brain Single Neuron Reconstruction Reveals Morphological Diversity in Molecularly Defined Claustral and Cortical Neuron Types
SSRN Electronic Journal 2019cited by 7position: middledoi
Early Induction of Oxidative Stress in Mouse Model of Alzheimer Disease with Reduced Mitochondrial Superoxide Dismutase Activity
PLoS ONE 2012cited by 61position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Xiongwei Zhu · University School1 papers (2012–2012)Xinglong Wang · Fudan University1 papers (2012–2012)Mark A. Smith · VistaGen Therapeutics (United States)1 papers (2012–2012)Hyun-Pil Lee · University School1 papers (2012–2012)Neel Pancholi · The University of Texas Health Science Center1 papers (2012–2012)Laura A. Previll · Case Western Reserve University1 papers (2012–2012)Hyoung‐gon Lee · The University of Texas at San Antonio1 papers (2012–2012)