Area of research
Immunology · Dermatology
Research interest
Research focused on Psoriasis and Immunology, with related work in Systemic lupus erythematosus, Gene silencing, Immune system. Notable publications include 'MORC Family ATPases Required for Heterochromatin Condensation and Gene Silencing', 'Cytokinocytes: the diverse contribution of keratinocytes to immune responses in skin', and 'Single cell and spatial sequencing define processes by which keratinocytes and fibroblasts amplify inflammatory responses in psoriasis'.
GWAS meta-analysis of psoriasis identifies new susceptibility alleles impacting disease mechanisms and therapeutic targets
Microvascular Endothelial Cells License APS Vasculopathy Through YAP1- and CCN2-Mediated Signaling
Systems-based identification of the Hippo pathway for promoting fibrotic mesenchymal differentiation in systemic sclerosis
Single cell and spatial sequencing define processes by which keratinocytes and fibroblasts amplify inflammatory responses in psoriasis
Single-cell sequencing reveals Hippo signaling as a driver of fibrosis in hidradenitis suppurativa
Single-cell profiling of prurigo nodularis demonstrates immune-stromal crosstalk driving profibrotic responses and reversal with nemolizumab
Nonlesional lupus skin contributes to inflammatory education of myeloid cells and primes for cutaneous inflammation
Single-cell transcriptomics reveals distinct effector profiles of infiltrating T cells in lupus skin and kidney
Phospholipase A2 enzymes represent a shared pathogenic pathway in psoriasis and pityriasis rubra pilaris
Cytokinocytes: the diverse contribution of keratinocytes to immune responses in skin
Contribution of plasma cells and B cells to hidradenitis suppurativa pathogenesis
KLK6 expression in skin induces PAR1-mediated psoriasiform dermatitis and inflammatory joint disease
MORC Family ATPases Required for Heterochromatin Condensation and Gene Silencing