Area of research
Molecular Biology · Surgery
Research interest
Research interests include Metabolomics and Mass Spectrometry Studies, Cholesterol and Lipid Metabolism, Cancer, Lipids, and Metabolism, and Lipid metabolism and biosynthesis.
Dietary control of peripheral adipose storage capacity through membrane lipid remodelling
Psychological stress increases skin infection through the action of TGFβ to suppress immune-acting fibroblasts
Bile acids regulate lipid metabolism through selective actions on fatty acid absorption
Stepwise neofunctionalization of the NF-κB family member Rel during vertebrate evolution
IL-10 constrains sphingolipid metabolism to limit inflammation
Dynamic lipidome alterations associated with human health, disease and ageing
CDKN2A deletion remodels lipid metabolism to prime glioblastoma for ferroptosis
Commensal <i>Cutibacterium acnes</i> induce epidermal lipid synthesis important for skin barrier function
Targeting de novo lipid synthesis induces lipotoxicity and impairs DNA damage repair in glioblastoma mouse models
Aster-dependent nonvesicular transport facilitates dietary cholesterol uptake
Acute activation of adipocyte lipolysis reveals dynamic lipid remodeling of the hepatic lipidome
Context-dependent regulation of ferroptosis sensitivity
FXR activation protects against NAFLD via bile-acid-dependent reductions in lipid absorption
Mitochondria-rough-ER contacts in the liver regulate systemic lipid homeostasis
A DMS Shotgun Lipidomics Workflow Application to Facilitate High-Throughput, Comprehensive Lipidomics
Cross-Laboratory Standardization of Preclinical Lipidomics Using Differential Mobility Spectrometry and Multiple Reaction Monitoring
Toll-Like Receptors Induce Signal-Specific Reprogramming of the Macrophage Lipidome
Interferon-mediated reprogramming of membrane cholesterol to evade bacterial toxins
Profiling of mouse macrophage lipidome using direct infusion shotgun mass spectrometry
Collaborative interactions of heterogenous ribonucleoproteins contribute to transcriptional regulation of sterol metabolism in mice
Transgenic tomatoes expressing the 6F peptide and ezetimibe prevent diet-induced increases of IFN-β and cholesterol 25-hydroxylase in jejunum
Transintestinal transport of the anti-inflammatory drug 4F and the modulation of transintestinal cholesterol efflux
Limiting Cholesterol Biosynthetic Flux Spontaneously Engages Type I IFN Signaling
Sterol regulatory element–binding proteins are essential for the metabolic programming of effector T cells and adaptive immunity
De-Repression of <i>PDGFRβ</i> Transcription Promotes Acquired Resistance to EGFR Tyrosine Kinase Inhibitors in Glioblastoma Patients
RAPID: Exposure Indices for COVID-19 Research
MRI: Acquisition of a 400 MHz Nuclear Magnetic Resonance (NMR) Spectrometer
Graduate Research Fellowship Program (GRFP)
Graduate Research Fellowship Program (GRFP)
Recruitment and retention of students in biotechnology-associated majors
SBIR Phase II: Novel Algorithms for Automated 3D Building Models and 3D Street Maps
SBIR Phase I: Novel Algorithms for Automated 3D Building Models and 3D Street Maps
Graduate Research Fellowship Program
Postdoctoral Research Fellowships in Chemistry