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Dag Leonard

Science for Life Laboratory · SE
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Area of research
Rheumatology · Pathology and Forensic Medicine
Research interest
Research focused on Immunology and Single-nucleotide polymorphism, with related work in Neutrophil extracellular traps, Autoantibody, Genetics. Notable publications include 'DNA methylation mapping identifies gene regulatory effects in patients with systemic lupus erythematosus', 'High genetic risk score is associated with early disease onset, damage accrual and decreased survival in systemic lupus erythematosus', and 'A single nucleotide polymorphism in the NCF1 gene leading to reduced oxidative burst is associated with systemic lupus erythematosus'.
h-index
citations
1,283
works
16
NIH funding
primary concept
email

Recent publications

Distinct HLA associations with autoantibody-defined subgroups in idiopathic inflammatory myopathies
EBioMedicine 2023cited by 18position: middledoi
Strong Association of Combined Genetic Deficiencies in the Classical Complement Pathway With Risk of Systemic Lupus Erythematosus and Primary Sjögren's Syndrome
Arthritis & Rheumatology 2022cited by 34position: middledoi
Four Systemic Lupus Erythematosus Subgroups, Defined by Autoantibodies Status, Differ Regarding <i>HLA‐DRB1</i> Genotype Associations and Immunological and Clinical Manifestations
ACR Open Rheumatology 2021cited by 59position: middledoi
Clinical Experience of Proteasome Inhibitor Bortezomib Regarding Efficacy and Safety in Severe Systemic Lupus Erythematosus: A Nationwide Study
Frontiers in Immunology 2021cited by 44position: middledoi
Molecular pathways in patients with systemic lupus erythematosus revealed by gene-centred DNA sequencing
Annals of the Rheumatic Diseases 2020cited by 66position: middledoi
High genetic risk score is associated with early disease onset, damage accrual and decreased survival in systemic lupus erythematosus
Annals of the Rheumatic Diseases 2019cited by 140position: lastdoi
Sex differences in clinical presentation of systemic lupus erythematosus
Biology of Sex Differences 2019cited by 125position: middledoi
Whole-genome sequencing identifies complex contributions to genetic risk by variants in genes causing monogenic systemic lupus erythematosus
Human Genetics 2019cited by 81position: middledoi
Genetic variations in A20 DUB domain provide a genetic link to citrullination and neutrophil extracellular traps in systemic lupus erythematosus
Annals of the Rheumatic Diseases 2019cited by 74position: middledoi
NCF1-339 polymorphism is associated with altered formation of neutrophil extracellular traps, high serum interferon activity and antiphospholipid syndrome in systemic lupus erythematosus
Annals of the Rheumatic Diseases 2019cited by 69position: middledoi
DNA methylation mapping identifies gene regulatory effects in patients with systemic lupus erythematosus
Annals of the Rheumatic Diseases 2018cited by 170position: middledoi
The STAT4 SLE risk allele rs7574865[T] is associated with increased IL-12-induced IFN-γ production in T cells from patients with SLE
Annals of the Rheumatic Diseases 2018cited by 100position: middledoi
Novel gene variants associated with cardiovascular disease in systemic lupus erythematosus and rheumatoid arthritis
Annals of the Rheumatic Diseases 2018cited by 58position: firstdoi
A single nucleotide polymorphism in the NCF1 gene leading to reduced oxidative burst is associated with systemic lupus erythematosus
Annals of the Rheumatic Diseases 2017cited by 140position: middledoi
Direct and indirect costs for systemic lupus erythematosus in Sweden. A nationwide health economic study based on five defined cohorts
Seminars in Arthritis and Rheumatism 2015cited by 46position: middledoi
HLA-DRB1*04/*13 alleles are associated with vascular disease and antiphospholipid antibodies in systemic lupus erythematosus
Annals of the Rheumatic Diseases 2012cited by 59position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Iva Gunnarsson · Karolinska University Hospital11 papers (2012–2021)Lars Rönnblom · Uppsala University11 papers (2012–2021)Anders Bengtsson · Lund University10 papers (2012–2021)Andreas Jönsen · Dalhousie University10 papers (2012–2021)Elisabet Svenungsson · Karolinska University Hospital10 papers (2012–2021)Christopher Sjöwall · Linköping University9 papers (2015–2021)Maija-Lena Eloranta · Uppsala University5 papers (2018–2019)Johanna K. Sandling · University of Manchester5 papers (2012–2019)Ann‐Christine Syvänen · Uppsala University5 papers (2012–2019)Solbritt Rantapää‐Dahlqvist · Science for Life Laboratory5 papers (2015–2019)Christine Bengtsson · Science for Life Laboratory4 papers (2015–2019)Gunnel Nordmark · University of Oklahoma Health Sciences Center4 papers (2012–2021)Johanna Gustafsson · Karolinska Institutet3 papers (2012–2021) · 3 papers (2018–2019)Agneta Zickert · Karolinska University Hospital3 papers (2012–2021)Leonid Padyukov · Karolinska Institutet3 papers (2012–2021)Andrei Alexsson · Science for Life Laboratory3 papers (2018–2019)Kerstin Elvin · Karolinska University Hospital2 papers (2012–2021)Karin Bolin · Science for Life Laboratory2 papers (2019–2019)Rikard Holmdahl · Uppsala University2 papers (2017–2019)
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