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Alexandre Detappe

Université Claude Bernard Lyon 1 · FR
🔎 Find collaborators in Biomedical Engineering · Pulmonary and Respiratory Medicine →
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Area of research
Biomedical Engineering · Pulmonary and Respiratory Medicine
Research interest
Research interests include Nanoplatforms for cancer theranostics, Radiation Therapy and Dosimetry, Advanced Radiotherapy Techniques, and Nanoparticle-Based Drug Delivery.
h-index
28
citations
3,843
works
124
NIH funding
primary concept
email

Recent publications

Functionalization of chitosan with a polycarboxylic macrocycle yields injectable hydrogel with pH and salts responsiveness
Materials Today Advances 2025cited by 7position: middledoi
Molecular bottlebrush prodrugs as mono- and triplex combination therapies for multiple myeloma
Nature Nanotechnology 2023cited by 100position: firstdoi
Subcutaneous Administration of a Zwitterionic Chitosan‐Based Hydrogel for Controlled Spatiotemporal Release of Monoclonal Antibodies
Advanced Materials 2023cited by 30position: lastdoi
Author Correction: Molecular bottlebrush prodrugs as mono- and triplex combination therapies for multiple myeloma
Nature Nanotechnology 2023cited by 2position: firstdoi
Author Correction: Molecular bottlebrush prodrugs as mono- and triplex combination therapies for multiple myeloma
Nature Nanotechnology 2023cited by 1position: firstdoi
Pro-organic radical contrast agents (“pro-ORCAs”) for real-time MRI of pro-drug activation in biological systems
Polymer Chemistry 2020cited by 32position: middledoi
Anti-MUC1-C Antibody–Conjugated Nanoparticles Potentiate the Efficacy of Fractionated Radiation Therapy
International Journal of Radiation Oncology*Biology*Physics 2020cited by 23position: firstdoi
Mitochondrial metabolism promotes adaptation to proteotoxic stress
Nature Chemical Biology 2019cited by 609position: middledoi
RETRACTED ARTICLE: Selective Priming of Tumor Blood Vessels by Radiation Therapy Enhances Nanodrug Delivery
Scientific Reports 2019cited by 23position: middledoi
Author Correction: Mitochondrial metabolism promotes adaptation to proteotoxic stress
Nature Chemical Biology 2019cited by 17position: middledoi
AGuIX<sup>®</sup> from bench to bedside—Transfer of an ultrasmall theranostic gadolinium-based nanoparticle to clinical medicine
British Journal of Radiology 2018cited by 134position: middledoi
Triply Loaded Nitroxide Brush-Arm Star Polymers Enable Metal-Free Millimetric Tumor Detection by Magnetic Resonance Imaging
ACS Nano 2018cited by 81position: middledoi
Ultrasmall Silica-Based Bismuth Gadolinium Nanoparticles for Dual Magnetic Resonance–Computed Tomography Image Guided Radiation Therapy
Nano Letters 2017cited by 137position: firstdoi
TIRR regulates 53BP1 by masking its histone methyl-lysine binding function
Nature 2017cited by 124position: middledoi
Nanoparticle conjugates of a highly potent toxin enhance safety and circumvent platinum resistance in ovarian cancer
Nature Communications 2017cited by 79position: middledoi
Stereotactic modulation of blood-brain barrier permeability to enhance drug delivery
Neuro-Oncology 2016cited by 343position: middledoi
Gadolinium-Based Nanoparticles and Radiation Therapy for Multiple Brain Melanoma Metastases: Proof of Concept before Phase I Trial
Theranostics 2016cited by 169position: middledoi
Advanced multimodal nanoparticles delay tumor progression with clinical radiation therapy
Journal of Controlled Release 2016cited by 87position: firstdoi
Key clinical beam parameters for nanoparticle-mediated radiation dose amplification
Scientific Reports 2016cited by 34position: firstdoi
Gadolinium Nanoparticles for Magnetic Resonance Guided Radiation Therapy
International Journal of Radiation Oncology*Biology*Physics 2016cited by 2position: firstdoi
Nanoparticle Mediated Tumor Vascular Disruption: A Novel Strategy in Radiation Therapy
Nano Letters 2015cited by 151position: middledoi
The use of theranostic gadolinium-based nanoprobes to improve radiotherapy efficacy
British Journal of Radiology 2014cited by 207position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Olivier Tillement · Université Claude Bernard Lyon 19 papers (2016–2025)Ross Berbeco · Northeastern University7 papers (2015–2019)Irene M. Ghobrial · Harvard University7 papers (2018–2023)Sijumon Kunjachan · Brigham and Women's Hospital7 papers (2015–2019)P. Peter Ghoroghchian · Massachusetts Institute of Technology6 papers (2017–2023)C. Mathieu · Université Claude Bernard Lyon 16 papers (2018–2023)Michael P. Agius · Broad Institute5 papers (2020–2023)Lucie Sancey · Université Claude Bernard Lyon 15 papers (2015–2019)François Lux · Université Claude Bernard Lyon 15 papers (2016–2025)Yivan Jiang · Massachusetts Institute of Technology5 papers (2018–2023)Hung V.‐T. Nguyen · Massachusetts Institute of Technology5 papers (2018–2023)Jeremiah A. Johnson · Massachusetts Institute of Technology5 papers (2018–2023)Wencong Wang · Massachusetts Institute of Technology4 papers (2020–2023)Sachin Bhagchandani · Massachusetts Institute of Technology3 papers (2023–2023)Nang Kham Su · Broad Institute3 papers (2023–2023)Douglas E. Biancur · New York University3 papers (2015–2016)Thomas Ireland · University of Chicago3 papers (2015–2019)David Lundberg · Massachusetts Institute of Technology3 papers (2023–2023)Shady Kotb · GlaxoSmithKline (Belgium)3 papers (2016–2019) · 3 papers (2016–2017)
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