Area of research
Molecular Biology · Pathology and Forensic Medicine
Research interest
Research focused on Cancer research and Tumor microenvironment, with related work in Colorectal cancer, Activin type 2 receptors, Stromal cell. Notable publications include 'Genetics and Genetic Biomarkers in Sporadic Colorectal Cancer', 'Biophysics of Tumor Microenvironment and Cancer Metastasis - A Mini Review', and 'Transforming Growth Factor β Superfamily Signaling in Development of Colorectal Cancer'.
Role of stromal activin A in human pancreatic cancer and metastasis in mice
Increased stiffness of the tumor microenvironment in colon cancer stimulates cancer associated fibroblast-mediated prometastatic activin A signaling
Nuclear translocation of Atox1 potentiates activin A-induced cell migration and colony formation in colon cancer
Serum Serotonin Differentiates Between Disease Activity States in Crohn’s Patients
Activin A Modulates Inflammation in Acute Pancreatitis and Strongly Predicts Severe Disease Independent of Body Mass Index
TGFβ and activin A in the tumor microenvironment in colorectal cancer
Biophysics of Tumor Microenvironment and Cancer Metastasis - A Mini Review
Clinical Assessment and Management of Portal Hypertension
Gut inflammation and dysbiosis in human motor neuron disease
NFkB is essential for activin-induced colorectal cancer migration via upregulation of PI3K-MDM2 pathway
TGFβ engages MEK/ERK to differentially regulate benign and malignant pancreas cell function
Activin signaling is an essential component of the TGF-β induced pro-metastatic phenotype in colorectal cancer
Increased Frequency of KRAS Mutations in African Americans Compared with Caucasians in Sporadic Colorectal Cancer
Superior Mesenteric Artery Syndrome: The Dark Side of Weight Loss
Multiorgan Failure Predicts Mortality in Emphysematous Pancreatitis
Transforming Growth Factor β Superfamily Signaling in Development of Colorectal Cancer
TGFβ Signaling in the Pancreatic Tumor Microenvironment Promotes Fibrosis and Immune Evasion to Facilitate Tumorigenesis
Loss of TGFβ signaling promotes colon cancer progression and tumor-associated inflammation
Expression of an Oncogenic BARD1 Splice Variant Impairs Homologous Recombination and Predicts Response to PARP-1 Inhibitor Therapy in Colon Cancer
PEDF inhibits pancreatic tumorigenesis by attenuating the fibro-inflammatory reaction
Genetics and Genetic Biomarkers in Sporadic Colorectal Cancer
Activin and TGFβ use diverging mitogenic signaling in advanced colon cancer
Molecular characterization of systemic sclerosis esophageal pathology identifies inflammatory and proliferative signatures
SIRT3 deacetylates and increases pyruvate dehydrogenase activity in cancer cells