Area of research
Molecular Biology · Cancer Research
Research interest
Professor Fiehn’s research aims at understanding metabolism on a comprehensive level in human population cohorts, animal and plant models, and cells and microorganisms. In order to leverage data from these diverse sets of biological systems, his research laboratory focuses on standardizing metabolomic reports and establishing metabolomic databases and libraries, for example the MassBank of North America that hosts over 200,000 public metabolite mass spectra and BinBase, a resource of over 90,000 samples covering more than 1,900 studies.
Best Practices in GC–MS and GC × GC–MS-Based Metabolomics and Volatile Analyses: An International Survey
A universal language for finding mass spectrometry data patterns
Implantation of engineered adipocytes suppresses tumor progression in cancer models
Discovery of metabolites prevails amid in-source fragmentation
A terminal metabolite of niacin promotes vascular inflammation and contributes to cardiovascular disease risk
High-Resolution Mass Spectrometry for Human Exposomics: Expanding Chemical Space Coverage
Peripheral inflammation is associated with brain atrophy and cognitive decline linked to mild cognitive impairment and Alzheimer’s disease
Introducing “Identification Probability” for Automated and Transferable Assessment of Metabolite Identification Confidence in Metabolomics and Related Studies
Microbiome-derived metabolites in early to mid-pregnancy and risk of gestational diabetes: a metabolome-wide association study
Predicting chronic postsurgical pain: current evidence and a novel program to develop predictive biomarker signatures
Adipocytes reprogram cancer cell metabolism by diverting glucose towards glycerol-3-phosphate thereby promoting metastasis
Effect of pentobarbital as a euthanasia agent on equine in vitro embryo production
Metabolomic and inflammatory signatures of symptom dimensions in major depression
Gut Microbiome-Linked Metabolites in the Pathobiology of Major Depression With or Without Anxiety—A Role for Bile Acids
An adaptive teosinte <i>mexicana</i> introgression modulates phosphatidylcholine levels and is associated with maize flowering time
Predictive Metabolomic Markers in Early to Mid-pregnancy for Gestational Diabetes Mellitus: A Prospective Test and Validation Study
Metabolite Damage and Damage Control in a Minimal Genome
A metabolomic signature of the APOE2 allele
Multi-Site Observational Study to Assess Biomarkers for Susceptibility or Resilience to Chronic Pain: The Acute to Chronic Pain Signatures (A2CPS) Study Protocol
Molecular damage in aging
Alterations in acylcarnitines, amines, and lipids inform about the mechanism of action of citalopram/escitalopram in major depression
Indoxyl sulfate, a gut microbiome-derived uremic toxin, is associated with psychic anxiety and its functional magnetic resonance imaging-based neurologic signature
Intestinal α1-2-Fucosylation Contributes to Obesity and Steatohepatitis in Mice
Duodenal Microbiome and Serum Metabolites Predict Hepatocellular Carcinoma in a Multicenter Cohort of Patients with Cirrhosis
Exposure to DMSO during infancy alters neurochemistry, social interactions, and brain morphology in long‐evans rats
A Cardiovascular Disease-Linked Gut Microbial Metabolite Acts via Adrenergic Receptors
A non-hallucinogenic psychedelic analogue with therapeutic potential
Adipocyte-Induced FABP4 Expression in Ovarian Cancer Cells Promotes Metastasis and Mediates Carboplatin Resistance
Metabolic Network Analysis Reveals Altered Bile Acid Synthesis and Metabolism in Alzheimer’s Disease
Serum triglycerides in Alzheimer disease