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Alvaro J. Alencar

University of Miami · US
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Area of research
Genetics · Pathology and Forensic Medicine
Research interest
Research interests include Chronic Lymphocytic Leukemia Research, Lymphoma Diagnosis and Treatment, CAR-T cell therapy research, and Cutaneous lymphoproliferative disorders research.
h-index
21
citations
2,376
works
151
NIH funding
primary concept
Medicine
email

Recent publications

Pirtobrutinib in Relapsed/Refractory (R/R) Mantle Cell Lymphoma (MCL): Final update from the Phase 1/2 BRUIN study
Blood 2025cited by 5position: middledoi
260 | UPDATED ANALYSIS OF A PHASE 2 MULTICENTER STUDY OF THE LONCASTUXIMAB IN RELAPSED/REFRACTORY MARGINAL ZONE LYMPHOMA DEMONSTRATES HIGH RATE OF COMPLETE RESPONSES
Hematological Oncology 2025cited by 1position: middledoi
Kinase-impaired BTK mutations are susceptible to clinical-stage BTK and IKZF1/3 degrader NX-2127
Science 2024cited by 143position: middledoi
Pirtobrutinib, a highly selective, non-covalent (reversible) BTK inhibitor in patients with B-cell malignancies: analysis of the Richter transformation subgroup from the multicentre, open-label, phase 1/2 BRUIN study
The Lancet Haematology 2024cited by 31position: middledoi
Efficacy and Safety of the Bruton's Tyrosine Kinase (BTK) Degrader NX-5948 in Patients with Relapsed/Refractory (R/R) Chronic Lymphocytic Leukemia (CLL): Updated Results from an Ongoing Phase 1a/b Study
Blood 2024cited by 24position: middledoi
Navigating the changing landscape of BTK-targeted therapies for B cell lymphomas and chronic lymphocytic leukaemia
Nature Reviews Clinical Oncology 2024cited by 21position: middledoi
Loncastuximab tesirine with rituximab in patients with relapsed or refractory follicular lymphoma: a single-centre, single-arm, phase 2 trial
The Lancet Haematology 2024cited by 21position: middledoi
Pirtobrutinib monotherapy in Bruton tyrosine kinase inhibitor-intolerant patients with B-cell malignancies: results of the phase I/II BRUIN trial
Haematologica 2024cited by 11position: middledoi
Five-year follow-up of a phase 2 study of ibrutinib plus fludarabine, cyclophosphamide, and rituximab as initial therapy in CLL
Blood Advances 2024cited by 9position: middledoi
Evaluation of bleeding risk in patients who received pirtobrutinib in the presence or absence of antithrombotic therapy
eJHaem 2024cited by 5position: middledoi
CLL-638 Latest Results From an Ongoing Firstin-Human Phase 1a/B Study of NX-5948, a Selective Bruton's Tyrosine Kinase (BTK) Degrader, in Patients With Relapsed/Refractory CLL and Other B-Cell Malignancies
Clinical Lymphoma Myeloma & Leukemia 2024cited by 2position: middledoi
Pembrolizumab and Involved Site Radiation Therapy Alone As an Alternative to Transplant in Patients with Localized Failure Following Chemotherapy for Hodgkin Lymphoma: A Prospective Multicenter Phase II Study
Blood 2024cited by 2position: middledoi
Pirtobrutinib after a Covalent BTK Inhibitor in Chronic Lymphocytic Leukemia
New England Journal of Medicine 2023cited by 205position: middledoi
Pirtobrutinib in Post-cBTKi CLL/SLL: ~30 Months Follow-up and Subgroup Analysis With/Without Prior BCL2i from the Phase 1/2 BRUIN Study
Blood 2023cited by 28position: middledoi
Pirtobrutinib in Relapsed/Refractory (R/R) Mantle Cell Lymphoma (MCL) Patients with Prior cBTKi: Safety and Efficacy Including High-Risk Subgroup Analyses from the Phase 1/2 BRUIN Study
Blood 2023cited by 17position: middledoi
Pirtobrutinib in Richter Transformation: Updated Efficacy and Safety Results with 18-Month Median Survival Follow-up from the Phase 1/2 BRUIN Study
Blood 2023cited by 11position: middledoi
Efficacy of Pirtobrutinib, a Highly Selective, Non-Covalent (Reversible) BTK Inhibitor in Richter Transformation: Results from the Phase 1/2 BRUIN Study
Blood 2022cited by 40position: middledoi
Efficacy of Pirtobrutinib in Covalent BTK-Inhibitor Pre-Treated Relapsed / Refractory Mantle Cell Lymphoma: Additional Patients and Extended Follow-up from the Phase 1/2 BRUIN Study
Blood 2022cited by 25position: middledoi
Efficacy of Pirtobrutinib in Covalent BTK-Inhibitor Pre-Treated Relapsed / Refractory CLL/SLL: Additional Patients and Extended Follow-up from the Phase 1/2 BRUIN Study
Blood 2022cited by 12position: middledoi
Updated Results from a Phase I/II Study of Duvelisib and Venetoclax in Patients with Relapsed or Refractory (R/R) Chronic Lymphocytic Leukemia (CLL) or Richter's Syndrome (RS)
Blood 2022cited by 8position: middledoi
Impact of severe acute respiratory syndrome coronavirus‐2 infection on the outcome of primary central nervous system lymphoma treatment: A study of the International PCNSL Collaborative Group
British Journal of Haematology 2022cited by 3position: middledoi
Impact on Tumour Treatment and Outcome of Sars-Cov-2 Infection in 91 Patients with Primary CNS Lymphoma: A Real-Life Study of the International PCNSL Collaborative Group
Blood 2022cited by 0position: middledoi
Pirtobrutinib in relapsed or refractory B-cell malignancies (BRUIN): a phase 1/2 study
The Lancet 2021cited by 450position: middledoi
Autologous Stem Cell Transplantation in the Management of Relapsed Non-Hodgkin Lymphoma
Journal of Clinical Oncology 2021cited by 18position: firstdoi
Pirtobrutinib, A Next Generation, Highly Selective, Non-Covalent BTK Inhibitor in Previously Treated CLL/SLL: Updated Results from the Phase 1/2 BRUIN Study
Blood 2021cited by 15position: middledoi
Pirtobrutinib, A Next Generation, Highly Selective, Non-Covalent BTK Inhibitor in Previously Treated Mantle Cell Lymphoma: Updated Results from the Phase 1/2 BRUIN Study
Blood 2021cited by 13position: middledoi
LOXO-305, A Next Generation, Highly Selective, Non-Covalent BTK Inhibitor in Previously Treated CLL/SLL: Results from the Phase 1/2 BRUIN Study
Blood 2020cited by 26position: middledoi
LOXO-305, A Next Generation, Highly Selective, Non-Covalent BTK Inhibitor in Previously Treated Mantle Cell Lymphoma, Waldenström's Macroglobulinemia, and Other Non-Hodgkin Lymphomas: Results from the Phase 1/2 BRUIN Study
Blood 2020cited by 11position: middledoi
Ibrutinib plus fludarabine, cyclophosphamide, and rituximab as initial treatment for younger patients with chronic lymphocytic leukaemia: a single-arm, multicentre, phase 2 trial
The Lancet Haematology 2019cited by 72position: middledoi
Short survival and frequent transformation in extranodal marginal zone lymphoma with multiple mucosal sites presentation
American Journal of Hematology 2019cited by 36position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Craig H. Moskowitz · City of Hope4 papers (2019–2025)Izidore S. Lossos · University of Miami4 papers (2018–2025)Juan Pablo Alderuccio · University of Miami4 papers (2019–2025)Jennifer L. Crombie · Dana-Farber/Harvard Cancer Center3 papers (2019–2024)David C. Fisher · Dana-Farber Cancer Institute3 papers (2019–2024)Svitlana Tyekucheva · Harvard University3 papers (2019–2024)Jennifer R. Brown · Harvard University3 papers (2019–2024)Isildinha M. Reis · University of Miami3 papers (2019–2025)Matthew S. Davids · Harvard University3 papers (2019–2024)Alexey V. Danilov · City Of Hope National Medical Center3 papers (2024–2024)Nirav N. Shah · Medical College of Wisconsin2 papers (2024–2024)Graham P. Collins · Churchill Hospital2 papers (2024–2024)Samuel Y. Ng · Memorial Sloan Kettering Cancer Center2 papers (2019–2024)Jon Arnason · Harvard University2 papers (2019–2024)Ronald W. Takvorian · Center for Cancer Research2 papers (2019–2024) · 2 papers (2024–2024)Josie Montegaard · Dana-Farber Cancer Institute2 papers (2022–2024)David Lessen · University of Miami2 papers (2024–2025)Ephraim P. Hochberg · University of Alabama at Birmingham2 papers (2019–2024)Caron A. Jacobson · Harvard University2 papers (2019–2024)
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