Area of research
Surgery · Oncology
Research interest
Research interests include Drug Transport and Resistance Mechanisms, Cholesterol and Lipid Metabolism, Lipoproteins and Cardiovascular Health, and Liver Disease Diagnosis and Treatment.
Neurobiology of eating behavior, nutrition, and health
A3907, a systemic ASBT inhibitor, improves cholestasis in mice by multiorgan activity and shows translational relevance to humans
Higher prevalence of coronary microvascular dysfunction in asymptomatic individuals with high levels of lipoprotein(a) with and without heterozygous familial hypercholesterolaemia
Of mice and men: murine bile acids explain species differences in the regulation of bile acid and cholesterol metabolism
An FXR Agonist Reduces Bile Acid Synthesis Independently of Increases in FGF19 in Healthy Volunteers
Asynchronous rhythms of circulating conjugated and unconjugated bile acids in the modulation of human metabolism
Treatment with the natural <scp>FXR</scp> agonist chenodeoxycholic acid reduces clearance of plasma <scp>LDL</scp> whilst decreasing circulating <scp>PCSK</scp>9, lipoprotein(a) and apolipoprotein C‐<scp>III</scp>
Circulating Hepcidin-25 Is Reduced by Endogenous Estrogen in Humans
Influence of physiological changes in endogenous estrogen on circulating PCSK9 and LDL cholesterol
Thyroid hormone reduces PCSK9 and stimulates bile acid synthesis in humans
Reductions in serum levels of <scp>LDL</scp> cholesterol, apolipoprotein B, triglycerides and lipoprotein(a) in hypercholesterolaemic patients treated with the liver‐selective thyroid hormone receptor agonist eprotirome
Gut Microbiota Regulates Bile Acid Metabolism by Reducing the Levels of Tauro-beta-muricholic Acid, a Naturally Occurring FXR Antagonist
Circulating Fibroblast Growth Factors as Metabolic Regulators—A Critical Appraisal
Circulating Human Hepcidin-25 Concentrations Display a Diurnal Rhythm, Increase with Prolonged Fasting, and Are Reduced by Growth Hormone Administration
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