Area of research
Immunology · Genetics
Research interest
Research interests include Inflammatory Bowel Disease, Immune Cell Function and Interaction, Immunotherapy and Immune Responses, and Cancer Immunotherapy and Biomarkers.
Spatial fibroblast niches define Crohn's fistulae.
Early-life Wnt4 expressing colon stromal cells orchestrate lifelong mucosal homeostasis via BMP-driven iNKT cell imprinting.
Human Enteric Glia Diversity in Health and Disease: New Avenues for the Treatment of Hirschsprung Disease.
Immune–epithelial–stromal networks define the cellular ecosystem of the small intestine in celiac disease
Immune-epithelial-stromal networks define the cellular ecosystem of the small intestine in celiac disease.
Author Correction: Spatial fibroblast niches define Crohn's fistulae.
Type I IFN-activated lung monocytes and macrophages as initiators and drivers of fibrosis at the alveolar barrier in IPF
Mechanisms and management of loss of response to anti-TNF therapy for patients with Crohn's disease: 3-year data from the prospective, multicentre PANTS cohort study.
Biologic Therapy for Inflammatory Bowel Disease: Real-World Comparative Effectiveness and Impact of Drug Sequencing in 13 222 Patients within the UK IBD BioResource.
Tracking in situ checkpoint inhibitor-bound target T cells in patients with checkpoint-induced colitis.
Goblet cell differentiation subgroups in colorectal cancer.
GSDMB is increased in IBD and regulates epithelial restitution/repair independent of pyroptosis.
Baseline Expression of Immune Gene Modules in Blood is Associated With Primary Response to Anti-TNF Therapy in Crohn's Disease Patients.
A Roadmap for the Human Gut Cell Atlas
A Roadmap for the Human Gut Cell Atlas
Intelectin-1 binds and alters the localization of the mucus barrier-modifying bacterium Akkermansia muciniphila.
Pathogenesis of Fistulating Crohn's Disease: A Review.
HLA-DP on Epithelial Cells Enables Tissue Damage by NKp44<sup>+</sup> Natural Killer Cells in Ulcerative Colitis.
A robust deep learning workflow to predict CD8 + T-cell epitopes.
Anti-TNF Biologicals Enhance the Anti-Inflammatory Properties of IgG N-Glycome in Crohn's Disease.
A systems approach evaluating the impact of SARS-CoV-2 variant of concern mutations on CD8+ T cell responses.
GSDMB is increased in IBD and regulates epithelial restitution/repair independent of pyroptosis
GSDMB is increased in IBD and regulates epithelial restitution/repair independent of pyroptosis
Large-scale sequencing identifies multiple genes and rare variants associated with Crohn's disease susceptibility.
Intelectin-1 binds and alters the localization of the mucus barrier–modifying bacterium <i>Akkermansia muciniphila</i>
Evaluating performance of existing computational models in predicting CD8+ T cell pathogenic epitopes and cancer neoantigens.
HLA-dependent variation in SARS-CoV-2 CD8 <sup>+</sup> T cell cross-reactivity with human coronaviruses.
Dual RNA sequencing reveals dendritic cell reprogramming in response to typhoidal Salmonella invasion.
Multicentre derivation and validation of a colitis-associated colorectal cancer risk prediction web tool.
Lymphatic endothelia stakeout cryptic stem cells.