Area of research
Hepatology · Epidemiology
Research interest
Research focused on Hepatitis C virus and Virology, with related work in Viral entry, Middle East respiratory syndrome coronavirus, Glycoprotein. Notable publications include 'Virology and cell biology of the hepatitis C virus life cycle – An update', 'Middle East respiratory syndrome coronavirus infection is inhibited by griffithsin', and 'Bidirectional genome-wide CRISPR screens reveal host factors regulating SARS-CoV-2, MERS-CoV and seasonal HCoVs'.
A coronavirus assembly inhibitor that targets the viral membrane protein
Bidirectional genome-wide CRISPR screens reveal host factors regulating SARS-CoV-2, MERS-CoV and seasonal HCoVs
An Arginine-Rich Motif in the ORF2 capsid protein regulates the hepatitis E virus lifecycle and interactions with the host cell
Ultrastructural modifications induced by SARS-CoV-2 in Vero cells: a kinetic analysis of viral factory formation, viral particle morphogenesis and virion release
Toll-like receptor 5 agonist flagellin reduces influenza A virus replication independently of type I interferon and interleukin 22 and improves antiviral efficacy of oseltamivir
Secretion of Hepatitis C Virus Replication Intermediates Reduces Activation of Toll-Like Receptor 3 in Hepatocytes
Middle East respiratory syndrome coronavirus infection is inhibited by griffithsin
Characterization of Hepatitis C Virus Interaction with Heparan Sulfate Proteoglycans
Hepatitis C Virus Envelope Glycoprotein E1 Forms Trimers at the Surface of the Virion
Virology and cell biology of the hepatitis C virus life cycle – An update
Successful anti-scavenger receptor class B type I (SR-BI) monoclonal antibody therapy in humanized mice after challenge with HCV variants with in vitro resistance to SR-BI-targeting agents
Identification of Conserved Residues in Hepatitis C Virus Envelope Glycoprotein E2 That Modulate Virus Dependence on CD81 and SRB1 Entry Factors
The antimalarial ferroquine is an inhibitor of hepatitis C virus
Additional Glycosylation Within a Specific Hypervariable Region of Subtype 3a of Hepatitis C Virus Protects Against Virus Neutralization
Disulfide Bonds in Hepatitis C Virus Glycoprotein E1 Control the Assembly and Entry Functions of E2 Glycoprotein