Area of research
Molecular Biology · Hematology
Research interest
Research interests include Single-cell and spatial transcriptomics, Acute Myeloid Leukemia Research, Zebrafish Biomedical Research Applications, and Hematopoietic Stem Cell Transplantation.
Metabolite-induced DNA damage drives stochastic stem cell loss and clonal hematopoiesis
Niche-derived Semaphorin 4A safeguards functional identity of myeloid-biased hematopoietic stem cells
A spatiotemporal atlas of mouse gastrulation and early organogenesis to explore axial patterning and project in vitro models onto in vivo space
Adaptation to ex vivo culture reduces human hematopoietic stem cell activity independently of the cell cycle
Genotoxic aldehyde stress prematurely ages hematopoietic stem cells in a p53-driven manner
Expression profiling of cerebrospinal fluid identifies dysregulated antiviral mechanisms in multiple sclerosis
Single-cell transcriptomics reveals the identity and regulators of human mast cell progenitors
Coagulation factor V is a T-cell inhibitor expressed by leukocytes in COVID-19
Single-cell multi-omics analysis of the immune response in COVID-19
Two Aldehyde Clearance Systems Are Essential to Prevent Lethal Formaldehyde Accumulation in Mice and Humans
Single‐cell molecular profiling provides a high‐resolution map of basophil and mast cell development
Single-cell chromatin accessibility maps reveal regulatory programs driving early mouse organogenesis
CHD7 and Runx1 interaction provides a braking mechanism for hematopoietic differentiation
Cohesin-dependent regulation of gene expression during differentiation is lost in cohesin-mutated myeloid malignancies
A single-cell hematopoietic landscape resolves 8 lineage trajectories and defects in Kit mutant mice
Combined Single-Cell Functional and Gene Expression Analysis Resolves Heterogeneity within Stem Cell Populations