Area of research
Molecular Biology · Genetics
Research interest
Research focused on Inflammation and Second messenger system, with related work in FOXP3, Microvesicles, In vivo. Notable publications include 'De novo fatty acid synthesis controls the fate between regulatory T and T helper 17 cells', 'Taxol-Loaded MSC-Derived Exosomes Provide a Therapeutic Vehicle to Target Metastatic Breast Cancer and Other Carcinoma Cells', and 'cGAS-like receptors sense RNA and control 3′2′-cGAMP signalling in Drosophila'.
Citraconate inhibits ACOD1 (IRG1) catalysis, reduces interferon responses and oxidative stress, and modulates inflammation and cell metabolism
Predicting butyrate- and propionate-forming bacteria of gut microbiota from sequencing data
Itaconate and derivatives reduce interferon responses and inflammation in influenza A virus infection
Thermosynechococcus switches the direction of phototaxis by a c-di-GMP-dependent process with high spatial resolution
Patatin-like phospholipase CapV in Escherichia coli - morphological and physiological effects of one amino acid substitution
cGAS-like receptors sense RNA and control 3′2′-cGAMP signalling in Drosophila
A meet-up of two second messengers: the c-di-AMP receptor DarB controls (p)ppGpp synthesis in Bacillus subtilis
Histamine can be Formed and Degraded in the Human and Mouse Heart
Establishment, Validation, and Initial Application of a Sensitive LC-MS/MS Assay for Quantification of the Naturally Occurring Isomers Itaconate, Mesaconate, and Citraconate
Minor pilins are involved in motility and natural competence in the cyanobacterium <i>Synechocystis</i> sp. PCC 6803
Natural Compound Library Screening Identifies New Molecules for the Treatment of Cardiac Fibrosis and Diastolic Dysfunction
The zoonotic pathogen Leptospira interrogans mitigates environmental stress through cyclic-di-GMP-controlled biofilm production
Taxol-Loaded MSC-Derived Exosomes Provide a Therapeutic Vehicle to Target Metastatic Breast Cancer and Other Carcinoma Cells
CyaC, a redox‐regulated adenylate cyclase of <i>Sinorhizobium meliloti</i> with a quinone responsive diheme‐B membrane anchor domain
Antiandrogenic Therapy With Finasteride Attenuates Cardiac Hypertrophy and Left Ventricular Dysfunction
cCMP and cUMP occur in vivo
De novo fatty acid synthesis controls the fate between regulatory T and T helper 17 cells
ExoY from Pseudomonas aeruginosa is a nucleotidyl cyclase with preference for cGMP and cUMP formation
From canonical to non-canonical cyclic nucleotides as second messengers: Pharmacological implications
cAMP, cGMP, cCMP and cUMP concentrations across the tree of life: High cCMP and cUMP levels in astrocytes
Nucleotidyl cyclase activity of soluble guanylyl cyclase in intact cells
Soluble adenylyl cyclase accounts for high basal cCMP and cUMP concentrations in HEK293 and B103 cells