Area of research
Immunology · Molecular Biology
Research interest
Research interests include Immune Cell Function and Interaction, Gut microbiota and health, IL-33, ST2, and ILC Pathways, and T-cell and B-cell Immunology.
Intestinal microbiota-derived short-chain fatty acids regulation of immune cell IL-22 production and gut immunity
Microbiota-derived short-chain fatty acids promote Th1 cell IL-10 production to maintain intestinal homeostasis
Commensal A4 bacteria inhibit intestinal Th2‐cell responses through induction of dendritic cell TGF‐β production
TGF‐β converts Th1 cells into Th17 cells through stimulation of Runx1 expression
TLR4 regulates IFN-γ and IL-17 production by both thymic and induced Foxp3+ Tregs during intestinal inflammation
<scp>ERK</scp> differentially regulates <scp>T</scp>h17‐ and <scp>T</scp>reg‐cell development and contributes to the pathogenesis of colitis
Downregulation of micro<scp>RNA</scp>‐107 in intestinal <scp>CD</scp>11c<sup>+</sup> myeloid cells in response to microbiota and proinflammatory cytokines increases <scp>IL</scp>‐23p19 expression
Th17 Cells Upregulate Polymeric Ig Receptor and Intestinal IgA and Contribute to Intestinal Homeostasis