H.B. Fuller (United States) · US
Area of research
Endocrinology, Diabetes and Metabolism · Psychiatry and Mental health
Research interest
Lew will be remembered internationally as a founder of the field of preventive cardiology, establishing cholesterol and blood pressure as risk factors for cardiovascular disease (CVD) and demonstrating that CVD is preventable through major national clinical trials such as Multiple Risk Factor Intervention Trial (MRFIT), the Systolic Hypertension in the Elderly Program (SHEP) and the WHI. He was one of the first to recognize the importance of menopause in women’s cardiovascular health, studying methods to reduce these risks. He was also instrumental in creating an Alzheimer’s research program at Pitt that led to meaningful insights into cognitive functioning in the elderly. Most recently, he was working to understand how cardiovascular disease can lead to Alzheimer’s disease, using the latest brain imaging and blood biomarkers.
Association of a Blood-Based Aging Biomarker Index With Death and Chronic Disease: Cardiovascular Health Study.
Association Between β-Amyloid Accumulation and Incident Dementia in Individuals 80 Years or Older Without Dementia.
Systolic Blood Pressure and Survival to Very Old Age: Results From the Women’s Health Initiative
Prospective Longitudinal Perfusion in Probable Alzheimer’s Disease Correlated with Atrophy in Temporal Lobe
Circulating plasma phospholipid fatty acid levels as a biomarker of habitual dietary fat intake: The INTERMAP/INTERLIPID Study
Systolic Blood Pressure and Survival to Very Old Age. Results from the Women’s Health Initiative
Longitudinal Changes in Hearing and Visual Impairments and Risk of Dementia in Older Adults in the United States
Association of Serum Neurofilament Light Chain Concentration and MRI Findings in Older Adults:The Cardiovascular Health Study
EUR Research Repository (Erasmus University Rotterdam) 2022cited by 21position: middle
Subjective cognitive decline and total energy intake: Talk too much?
Association of Thyroid Dysfunction With Cognitive Function
Peripheral inflammatory biomarkers predict the deposition and progression of amyloid-β in cognitively unimpaired older adults.
Dietary cholesterol and egg intake in relation to incident cardiovascular disease and all-cause and cause-specific mortality in postmenopausal women.
Metabolically Healthy/Unhealthy Overweight/Obesity Associations With Incident Heart Failure in Postmenopausal Women
Twenty-seven-year time trends in dementia incidence in Europe and the United States
Association of Menopausal Hormone Therapy With Breast Cancer Incidence and Mortality During Long-term Follow-up of the Women’s Health Initiative Randomized Clinical Trials
Association Between Depressive Symptoms and Incident Cardiovascular Diseases
Estrogen, brain structure, and cognition in p<scp>ostmenopausal</scp>women
Relationship of amyloid-β1-42 in blood and brain amyloid: Ginkgo Evaluation of Memory Study.
Cardiovascular Risk Factors Associated With Venous Thromboembolism
Preventing dementia by preventing stroke: The Berlin Manifesto
Metabolic syndrome and risk of endometrial cancer in postmenopausal women: a prospective study
APOL1 Kidney Risk Variants and Cardiovascular Disease: An Individual Participant Data Meta-Analysis
Equalization of four cardiovascular risk algorithms after systematic recalibration: individual-participant meta-analysis of 86 prospective studies
Risk thresholds for alcohol consumption: combined analysis of individual-participant data for 599 912 current drinkers in 83 prospective studies
Low-Fat Dietary Pattern and Cancer Mortality in the Women’s Health Initiative (WHI) Randomized Controlled Trial
Association of Coronary Artery Calcium Score vs Age With Cardiovascular Risk in Older Adults
Both Light Intensity and Moderate‐to‐Vigorous Physical Activity Measured by Accelerometry Are Favorably Associated With Cardiometabolic Risk Factors in Older Women: The Objective Physical Activity and Cardiovascular Health (OPACH) Study
Trans-ethnic fine-mapping of genetic loci for body mass index in the diverse ancestral populations of the Population Architecture using Genomics and Epidemiology (PAGE) Study reveals evidence for multiple signals at established loci
Transethnic insight into the genetics of glycaemic traits: fine-mapping results from the Population Architecture using Genomics and Epidemiology (PAGE) consortium
Trends in the incidence of dementia: design and methods in the Alzheimer Cohorts Consortium