Area of research
Neurology · Immunology
Research interest
Research interests include Neuroinflammation and Neurodegeneration Mechanisms, Inflammation biomarkers and pathways, Alzheimer's disease research and treatments, and Neurological Disease Mechanisms and Treatments.
Alzheimer risk-increasing TREM2 variant causes aberrant cortical synapse density and promotes network hyperexcitability in mouse models
AD-linked R47H-<i>TREM2</i>mutation induces disease-enhancing microglial states via AKT hyperactivation
Proximal recolonization by self-renewing microglia re-establishes microglial homeostasis in the adult mouse brain
Microglial microRNAs mediate sex-specific responses to tau pathology
Differential effects of partial and complete loss of TREM2 on microglial injury response and tauopathy
Microglial NFκB-TNFα hyperactivation induces obsessive–compulsive behavior in mouse models of progranulin-deficient frontotemporal dementia
Critical data‐based re‐evaluation of minocycline as a putative specific microglia inhibitor
SIRT1 Deficiency in Microglia Contributes to Cognitive Decline in Aging and Neurodegeneration via Epigenetic Regulation of IL-1β