Area of research
Immunology · Infectious Diseases
Research interest
Research interests include Immune cells in cancer, COVID-19 Clinical Research Studies, Immune Cell Function and Interaction, and T-cell and B-cell Immunology.
Autophagy acts as a brake on obesity-related fibrosis by controlling purine nucleoside signalling.
A single cell atlas of frozen shoulder capsule identifies features associated with inflammatory fibrosis resolution.
IFNγ signaling in cytotoxic T cells restricts anti-tumor responses by inhibiting the maintenance and diversity of intra-tumoral stem-like T cells.
Spatial transcriptomic characterization of COVID-19 pneumonitis identifies immune circuits related to tissue injury
Publisher Correction: Lipid-associated macrophages transition to an inflammatory state in human atherosclerosis, increasing the risk of cerebrovascular complications.
Erratum: Author Correction: Lipid-associated macrophages transition to an inflammatory state in human atherosclerosis, increasing the risk of cerebrovascular complications.
A blood atlas of COVID-19 defines hallmarks of disease severity and specificity.
An immunodominant NP<sub>105-113</sub>-B*07:02 cytotoxic T cell response controls viral replication and is associated with less severe COVID-19 disease.
Secondary influenza challenge triggers resident memory B cell migration and rapid relocation to boost antibody secretion at infected sites
Variants in <i>ALDH1A2</i> reveal an anti-inflammatory role for retinoic acid and a new class of disease-modifying drugs in osteoarthritis.
IL-1-driven stromal–neutrophil interactions define a subset of patients with inflammatory bowel disease that does not respond to therapies
IL-1-driven stromal-neutrophil interactions define a subset of patients with inflammatory bowel disease that does not respond to therapies.
Identification of LZTFL1 as a candidate effector gene at a COVID-19 risk locus.
Deconvolution of monocyte responses in inflammatory bowel disease reveals an IL-1 cytokine network that regulates IL-23 in genetic and acquired IL-10 resistance.
Single cell analysis of spondyloarthritis regulatory T cells identifies distinct synovial gene expression patterns and clonal fates.
RBFOX splicing factors contribute to a broad but selective recapitulation of peripheral tissue splicing patterns in the thymus.
Spatial transcriptomic characterization of COVID-19 pneumonitis identifies immune circuits related to tissue injury
Distinct synovial tissue macrophage subsets regulate inflammation and remission in rheumatoid arthritis
Distinct synovial tissue macrophage subsets regulate inflammation and remission in rheumatoid arthritis.
Deconvolution of monocyte responses in inflammatory bowel disease reveals an IL-1 cytokine network that regulates IL-23 in genetic and acquired IL-10 resistance
GM-CSF drives dysregulated hematopoietic stem cell activity and pathogenic extramedullary myelopoiesis in experimental spondyloarthritis.
IRF5 guides monocytes toward an inflammatory CD11c<sup>+</sup> macrophage phenotype and promotes intestinal inflammation.
IL-33 promotes anemia during chronic inflammation by inhibiting differentiation of erythroid progenitors.
Cellular census of human fibrosis defines functionally distinct stromal cell types and states.
Ciliary proteins specify the cell inflammatory response by tuning NFκB signalling, independently of primary cilia.
Author Correction: Cellular census of human fibrosis defines functionally distinct stromal cell types and states.
Distinct fibroblast subsets drive inflammation and damage in arthritis
The Short Chain Fatty Acid Butyrate Imprints an Antimicrobial Program in Macrophages.
Distinct fibroblast subsets drive inflammation and damage in arthritis.
CGAT-core: a python framework for building scalable, reproducible computational biology workflows