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Lukas Flatz

University of St.Gallen ·
Area of research
Oncology · Immunology
Research interest
Research interests include Cancer Immunotherapy and Biomarkers, Cutaneous Melanoma Detection and Management, Immunotherapy and Immune Responses, and Nonmelanoma Skin Cancer Studies.
h-index
46
citations
7,703
works
287
NIH funding
primary concept
email

Recent publications

Adjuvant Cemiplimab or Placebo in High-Risk Cutaneous Squamous-Cell Carcinoma
New England Journal of Medicine 2025cited by 49position: middledoi
HLA-A*01:01-B*08:01-C*07:01 is linked to early-onset immune checkpoint inhibitor-induced myositis and myocarditis
Journal for ImmunoTherapy of Cancer 2025cited by 3position: middledoi
Phase 3 study (PIVOTAL) of neoadjuvant intralesional daromun vs. immediate surgery in fully resectable melanoma with regional skin and/or nodal metastases.
Journal of Clinical Oncology 2024cited by 30position: middledoi
Tumour-informed liquid biopsies to monitor advanced melanoma patients under immune checkpoint inhibition
Nature Communications 2024cited by 18position: middledoi
Multimodal Profiling of Peripheral Blood Identifies Proliferating Circulating Effector CD4+ T Cells as Predictors for Response to Integrin α4β7–Blocking Therapy in Inflammatory Bowel Disease
Gastroenterology 2024cited by 17position: middledoi
Autoimmunity Against Surfactant Protein B Is Associated with Pneumonitis During Checkpoint Blockade
American Journal of Respiratory and Critical Care Medicine 2024cited by 5position: lastdoi
Étude de phase 3 (PIVOTAL) sur le daromun intralésionnel néoadjuvant comparé à une chirurgie immédiate dans le mélanome entièrement résécable avec métastases cutanées régionales et/ou ganglionnaires
Annales de Dermatologie et de Vénéréologie - FMC 2024cited by 0position: middledoi
Acidosis-mediated increase in IFN-γ-induced PD-L1 expression on cancer cells as an immune escape mechanism in solid tumors
Molecular Cancer 2023cited by 72position: middledoi
Adjuvant immunotherapy with nivolumab versus observation in completely resected Merkel cell carcinoma (ADMEC-O): disease-free survival results from a randomised, open-label, phase 2 trial
The Lancet 2023cited by 67position: middledoi
Interleukin 17 signaling supports clinical benefit of dual CTLA-4 and PD-1 checkpoint inhibition in melanoma
Nature Cancer 2023cited by 59position: middledoi
<i>In vivo</i> imaging of CD8<sup>+</sup> T cells in metastatic cancer patients: first clinical experience with simultaneous [<sup>89</sup>Zr]Zr-Df-IAB22M2C PET/MRI
Theranostics 2023cited by 17position: middledoi
Histopathologic regression in patients with primary cutaneous melanoma undergoing sentinel lymph node biopsy is associated with favorable survival and, after metastasis, with improved progression-free survival on immune checkpoint inhibitor therapy: A single-institutional cohort study
Journal of the American Academy of Dermatology 2023cited by 9position: lastdoi
Histopathologic abundance of pigmentation correlates with disease‐specific survival in malignant melanoma but is not independent of current <scp>AJCC pT</scp> stage
Pigment Cell & Melanoma Research 2023cited by 5position: middledoi
Baseline metastatic growth rate is an independent prognostic marker in patients with advanced BRAF V600 mutated melanoma receiving targeted therapy
European Journal of Cancer 2023cited by 3position: lastdoi
Author Correction: Interleukin 17 signaling supports clinical benefit of dual CTLA-4 and PD-1 checkpoint inhibition in melanoma
Nature Cancer 2023cited by 2position: middledoi
Prognosis of Patients With Primary Melanoma Stage I and II According to American Joint Committee on Cancer Version 8 Validated in Two Independent Cohorts: Implications for Adjuvant Treatment
Journal of Clinical Oncology 2022cited by 99position: middledoi
Autoreactive napsin A–specific T cells are enriched in lung tumors and inflammatory lung lesions during immune checkpoint blockade
Science Immunology 2022cited by 39position: lastdoi
Vitamin C Deficiency in Blood Samples of COVID-19 Patients
Antioxidants 2022cited by 15position: middledoi
Genome-Wide Association Study Suggests the Variant rs7551288*A within the DHCR24 Gene Is Associated with Poor Overall Survival in Melanoma Patients
Cancers 2022cited by 4position: middledoi
Preexisting and Post–COVID-19 Immune Responses to SARS-CoV-2 in Patients with Cancer
Cancer Discovery 2021cited by 47position: middledoi
Association between Immune-Related Adverse Events and Survival in 319 Stage IV Melanoma Patients Treated with PD-1-Based Immunotherapy: An Approach Based on Clinical Chemistry
Cancers 2021cited by 25position: middledoi
Early disappearance of tumor antigen-reactive T cells from peripheral blood correlates with superior clinical outcomes in melanoma under anti-PD-1 therapy
Journal for ImmunoTherapy of Cancer 2021cited by 15position: middledoi
Pretreatment metastatic growth rate determines clinical outcome of advanced melanoma patients treated with anti-PD-1 antibodies: a multicenter cohort study
Journal for ImmunoTherapy of Cancer 2021cited by 15position: middledoi
Keratinocyte differentiation antigen-specific T cells in immune checkpoint inhibitor-treated NSCLC patients are associated with improved survival
OncoImmunology 2021cited by 8position: lastdoi
IgA autoantibodies target pulmonary surfactant in patients with severe COVID-19
medRxiv 2021cited by 6position: lastdoi
CD155 on Tumor Cells Drives Resistance to Immunotherapy by Inducing the Degradation of the Activating Receptor CD226 in CD8+ T Cells
Immunity 2020cited by 175position: middledoi
Association of Checkpoint Inhibitor–Induced Toxic Effects With Shared Cancer and Tissue Antigens in Non–Small Cell Lung Cancer
JAMA Oncology 2019cited by 392position: lastdoi
Microbiota-derived peptide mimics drive lethal inflammatory cardiomyopathy
Science 2019cited by 260position: middledoi
Association Between Immune-Related Adverse Events During Anti–PD-1 Therapy and Tumor Mutational Burden
JAMA Oncology 2019cited by 130position: lastdoi
Neutrophil-to-Lymphocyte ratio (NLR) and Platelet-to-Lymphocyte ratio (PLR) as prognostic markers in patients with non-small cell lung cancer (NSCLC) treated with nivolumab
Lung Cancer 2017cited by 1,013position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Thomas Eigentler · University of Tübingen8 papers (2021–2024)Claus Garbe · STZ eyetrial7 papers (2021–2024)Andrea Forschner · University Children's Hospital Tübingen5 papers (2021–2024)Teresa Amaral · University Hospital and Clinics4 papers (2021–2023)Tobias Sinnberg · University Children's Hospital Tübingen3 papers (2021–2022)Nikolaus B. Wagner · Kantonsspital St. Gallen3 papers (2021–2023)Friedegund Meier · University Cancer Center Hamburg3 papers (2021–2024) · 3 papers (2019–2025)Ulrike Leiter · University of Tübingen3 papers (2021–2023)Martin Röcken · German Cancer Research Center2 papers (2021–2023)Patrick Terheyden · Martin Luther University Halle-Wittenberg2 papers (2021–2023)Oltin T. Pop · University of St.Gallen2 papers (2021–2021)Gisela Metzler · University of Tübingen2 papers (2023–2023)Stephan Forchhammer · Universitätsklinikum Tübingen2 papers (2023–2023)Michele Maio · Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori2 papers (2024–2024) · 2 papers (2021–2022)David Bomze · Hebrew University of Jerusalem2 papers (2019–2021)Caroline Gaudy‐Marqueste · Centre National de la Recherche Scientifique2 papers (2024–2024)Peter Martus · Institute for Applied Economic Research2 papers (2021–2024) · 2 papers (2024–2024)