Area of research
Cardiology and Cardiovascular Medicine · Surgery
Research interest
Our researchers have also led a number of international multicenter, randomized clinical trials, including the Should We Emergently Revascularize Occluded Coronaries for Cardiogenic Shock (SHOCK) trial , the SHOCK-2 phase II trial , and the Tilarginine Acetate Injection in a Randomized International Study in Unstable MI Patients with Cardiogenic Shock (TRIUMPH) phase III trial . These National Heart, Lung, and Blood Institute (NHLBI) Small Business Innovation Research program–funded trials were the first to test a novel pharmacologic agent for refractory cardiogenic shock.
Additive prognostic value of functional performance to coronary artery anatomy: the ISCHEMIA trial
Stress Cardiac Magnetic Resonance Ischemia Burden and Cardiovascular Events
Residual Angina Following Complete Revascularization in the ISCHEMIA Trial: Frequency, Clinical Characteristics, Health Status, and Cardiovascular Outcomes
Multi-modality Imaging to Determine Underlying Causes of MINOCA in Women and Men.
Guideline-Directed Medical Therapy and Outcomes in the ISCHEMIA Trial
Guideline-Directed Medical Therapy and Outcomes in the ISCHEMIA Trial
Invasive vs Conservative Management of Patients With Chronic Total Occlusion
A Framework for Exception From Informed Consent in Trials Enrolling Patients With ST‐Segment–Elevation Myocardial Infarction and Cardiogenic Shock
Health Status Outcomes With Percutaneous Coronary Intervention and Coronary Artery Bypass Grafting in ISCHEMIA
Evaluating the Appropriate Use Criteria for Coronary Revascularization in Stable Ischemic Heart Disease Using Randomized Data From the ISCHEMIA Trial
Comparative Prognosis by Stress ECG and Stress Imaging
Brief Mindfulness-Based Cognitive Therapy in Women With Myocardial Infarction
Myocardial Infarction Platelet Gene Expression Signatures in Women.
Sex Differences in Psychosocial Factors and Angina in Patients With Chronic Coronary Disease.
Management of Ischemic Heart Disease in Patients With Heart Failure: JACC: Heart Failure Position Statement.
Trajectories of Angina After Initial Invasive vs Conservative Strategy for Chronic Coronary Disease.
Platelets induce endothelial cell mitochondrial dysfunction in myocardial infarction.
Real-World Evidence Linking the Predicting Risk of Cardiovascular Disease Events Risk Score and Coronary Artery Calcium.
Current Concepts in Revascularization for Ischemic Heart Disease With Reduced Ejection Fraction.
Clonal Hematopoiesis of Indeterminate Potential in Chronic Coronary Disease: A Report From the ISCHEMIA Trials Biorepository.
Quantitative Coronary Artery Plaque Parameters and Severity of Ischemia in Patients With INOCA.
On-Treatment Change in d-Dimer Is Associated With Differential Outcomes Among Therapeutic Dose Heparin-Treated Noncritically Ill Patients Hospitalized for COVID-19.
Abstract 4369684: Mitochondrial DNA Copy Number (mtDNA-CN): Associations with Mortality and Gene Expression in the International Study of Comparative Health Effectiveness with Medical and Invasive Approaches (ISCHEMIA) Biorepository
Abstract 4366483: Multi-omic Characterization of Clonal Hematopoiesis of Indeterminate Potential (CHIP) in the ISCHEMIA (International Study of Comparative Health Effectiveness with Medical and Invasive Approaches) Trials Biorepository
Atherosclerosis quantification and cardiovascular risk: the ISCHEMIA trial
A Platelet Reactivity ExpreSsion Score derived from patients with peripheral artery disease predicts cardiovascular risk
A Platelet Reactivity ExpreSsion Score derived from patients with peripheral artery disease predicts cardiovascular risk.
Variation in Health Status With Invasive vs Conservative Management of Chronic Coronary Disease
Sex Differences in Revascularization, Treatment Goals, and Outcomes of Patients With Chronic Coronary Disease: Insights From the ISCHEMIA Trial
Sex Differences in Revascularization, Treatment Goals, and Outcomes of Patients With Chronic Coronary Disease: Insights From the ISCHEMIA Trial