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Harlan M. Krumholz

Yale University · US
Area of research
Cardiology and Cardiovascular Medicine · Economics and Econometrics
Research interest
Dr. Krumholz has been honored by membership in the National Academy of Medicine, the Association of American Physicians, and the American Society for Clinical Investigation. He was named a Distinguished Scientist of the American Heart Association and received their Award of Meritorious Achievement and Clinical Research Prize. He served as a member of the Advisory Committee to the Director of the National Institutes of Health. Dr. Krumholz received the Friendship Award from the People’s Republic of China in recognition of his collaborative efforts to develop a national cardiovascular research network and was named by the Chinese Society of Cardiology as a Top-10 Distinguished International Cardiologist for his contributions to the development of cardiovascular medicine in China. He founded the American Heart Association’s Quality of Care and Outcomes Research Council and co-founded their annual conference. He was the founding editor of Circulation: Cardiovascular Quality and Outcomes; founding editor of CardioExchange, a social media site of the publisher of the New England Journal of Medicine; and editor of Journal Watch Cardiology of the New England Journal of Medicine. He was a founding Governor of the Patient-Centered Outcomes Research Institute. He is the Editor-in-Chief of JACC, a pre-eminent cardiovascular medical journal.
h-index
216
citations
212,746
works
2,800
NIH funding
primary concept
email

Recent publications

Principles to guide clinical AI readiness and move from benchmarks to real-world evaluation
Nature Medicine 2026cited by 4position: contributordoi
Antiphospholipid antibodies and cardiovascular thrombosis
Nature Reviews Cardiology 2026cited by 2position: contributordoi
Artificial intelligence-based automated interpretation of images of electrocardiograms: development and multinational validation of ECG-GPT
European Heart Journal - Digital Health 2026cited by 1position: contributordoi
Real-world evidence for comparative safety of second-line antihyperglycemic agents in older adults with type 2 diabetes
Nature Communications 2026cited by 0position: contributordoi
Assessing the Secondary Use and Scientific Impact of Shared Clinical Trial Data: A Cross-Sectional Study of Clinical Trials Shared on the YODA Project Platform
2026cited by 0position: contributordoi
Primary Prevention Antihypertensive Eligibility With the 2025 AHA/ACC Guideline
Hypertension 2026cited by 0position: contributordoi
Exploratory analyses of Immunologic Features in a Randomized, Placebo-Controlled Trial of Nirmatrelvir/Ritonavir for Long COVID
2026cited by 0position: contributordoi
Clinical Trial Patient Matching: A Real-Time, Common Data Model and Artificial Intelligence–Driven System for Semiautomated Patient Prescreening in Cancer Clinical Trials
JCO Clinical Cancer Informatics 2026cited by 0position: contributordoi
Sex differences in all-cause and cause-specific mortality and years of life lost in the United States, 2000-2023
The American Journal of Medicine 2026cited by 0position: contributordoi
Spatial and racial/ethnic disparities in cardiovascular mortality attributable to PM <sub>2.5</sub> components in the contiguous United States
Science Advances 2026cited by 0position: contributordoi
Missed Opportunities for Stroke Prevention in Hypertensive Patients: A Retrospective Case-Control Study
2026cited by 0position: contributordoi
Heart failure risk stratification using artificial intelligence applied to electrocardiogram images: a multinational study
European Heart Journal 2025cited by 51position: contributordoi
Targeting the SARS-CoV-2 reservoir in long COVID
The Lancet Infectious Diseases 2025cited by 48position: middledoi
Artificial Intelligence–Enhanced Risk Stratification of Cancer Therapeutics–Related Cardiac Dysfunction Using Electrocardiographic Images
Circulation: Cardiovascular Quality and Outcomes 2025cited by 38position: contributordoi
Artificial Intelligence–Enabled Prediction of Heart Failure Risk From Single-Lead Electrocardiograms
JAMA Cardiology 2025cited by 37position: middledoi
Nirmatrelvir–ritonavir versus placebo–ritonavir in individuals with long COVID in the USA (PAX LC): a double-blind, randomised, placebo-controlled, phase 2, decentralised trial
The Lancet Infectious Diseases 2025cited by 30position: lastdoi
Immunological and Antigenic Signatures Associated with Chronic Illnesses after COVID-19 Vaccination
2025cited by 23position: contributordoi
Artificial intelligence-enabled electrocardiography and echocardiography to track preclinical progression of transthyretin amyloid cardiomyopathy
European Heart Journal 2025cited by 21position: contributordoi
Development and multinational validation of an ensemble deep learning algorithm for detecting and predicting structural heart disease using noisy single-lead electrocardiograms
European Heart Journal - Digital Health 2025cited by 18position: middledoi
The PAX LC Trial: A Decentralized, Phase 2, Randomized, Double-Blind Study of Nirmatrelvir/Ritonavir Compared with Placebo/Ritonavir for Long COVID
The American Journal of Medicine 2025cited by 17position: contributordoi
Development and multinational validation of an ensemble deep learning algorithm for detecting and predicting structural heart disease using noisy single-lead electrocardiograms
European Heart Journal - Digital Health 2025cited by 16position: contributordoi
Identification of hypertrophic cardiomyopathy on electrocardiographic images with deep learning
Nature Cardiovascular Research 2025cited by 11position: contributordoi
JACC Data Report
Journal of the American College of Cardiology 2025cited by 11position: middledoi
Floods and cause-specific mortality in the United States applying a triply robust approach
Nature Communications 2025cited by 8position: contributordoi
Cost-effectiveness of iptacopan for paroxysmal nocturnal hemoglobinuria
Blood 2025cited by 8position: contributordoi
Improvements in Cardiometabolic Risk Factors by Weight Reduction: A Post Hoc Analysis of Adults With Obesity Randomly Assigned to Tirzepatide
Annals of Internal Medicine 2025cited by 7position: contributordoi
Long COVID Characteristics and Experience: A Descriptive Study From the Yale LISTEN Research Cohort
The American Journal of Medicine 2025cited by 7position: contributordoi
Impact of COVID-19 vaccination on symptoms and immune phenotypes in vaccine-naïve individuals with Long COVID
Communications Medicine 2025cited by 7position: middledoi
Internal Tremors and Vibrations in Long COVID: A Cross-Sectional Study
The American Journal of Medicine 2025cited by 6position: contributordoi
Joint Exposure to Ozone and Temperature and Acute Myocardial Infarction Among Adults Aged 18 to 64 Years in the United States
Circulation 2025cited by 6position: contributordoi

Grants

No grants ingested yet.

Frequent collaborators

· 279 papers (2019–2026)Rohan Khera · Institute for Medical Informatics and Biostatistics60 papers (2019–2026)Yuan Lu · Yale New Haven Hospital55 papers (2020–2026)César Caraballo · Centre for Advancing Health Outcomes30 papers (2020–2026)John A. Spertus · University of Glasgow27 papers (2012–2025)Lovedeep S. Dhingra · Yale New Haven Hospital24 papers (2022–2026)Evangelos K. Oikonomou · British Heart Foundation23 papers (2022–2026)Joseph S. Ross · Yale University22 papers (2019–2026)Bobak J. Mortazavi · Icahn School of Medicine at Mount Sinai21 papers (2020–2026)Wade L. Schulz · University of Florida20 papers (2019–2026)Arya Aminorroaya · Saint Luke's Hospital19 papers (2022–2026)Erica S. Spatz · Stanford University18 papers (2019–2026)Shiwani Mahajan · Brigham and Women's Hospital18 papers (2020–2025)Zhenqiu Lin · Center for Outcomes Research and Clinical Epidemiology17 papers (2019–2024)Jeremy Samuel Faust · New York University15 papers (2020–2024)Rohan Khera · Yale New Haven Hospital15 papers (2021–2025)Daisy Massey · University of Massachusetts Chan Medical School13 papers (2020–2022)Rachel P. Dreyer · Apple (Israel)13 papers (2019–2025)Mitsuaki Sawano · Tokyo Dental College12 papers (2022–2026)Akiko Iwasaki · Yale University12 papers (2021–2025)