Area of research
Pulmonary and Respiratory Medicine · Molecular Biology
Research interest
Research focused on Cancer research and Gene silencing, with related work in Cancer, CD8, Metastasis. Notable publications include 'Shared and distinct biological circuits in effector, memory and exhausted CD8+ T cells revealed by temporal single-cell transcriptomics and epigenetics', 'Morbidity and Mortality of Laparoscopic vs Open Total Gastrectomy for Clinical Stage I Gastric Cancer', and 'In vivo CD8+ T cell CRISPR screening reveals control by Fli1 in infection and cancer'.
Investigation of the pan-cancer property of SDC1 and its expression pattern affected patients’ overall survival for breast cancer
Perioperative versus adjuvant S-1 plus oxaliplatin chemotherapy for stage II/III resectable gastric cancer (RESONANCE): a randomized, open-label, phase 3 trial
Histone demethylase KDM4A mediating macrophage polarization: A potential mechanism of trichloroethylene induced liver injury
[Incidence of postoperative complications in Chinese patients with gastric or colorectal cancer based on a national, multicenter, prospective, cohort study].
Stat5 opposes the transcription factor Tox and rewires exhausted CD8+ T cells toward durable effector-like states during chronic antigen exposure
Macrophage autophagy contributes to immune liver injury in trichloroethylene sensitized mice: Critical role of TNF‐α mediating mTOR pathway
Decreased expression of SCARA5 predicts a poor prognosis in melanoma using bioinformatics analysis
Construction of a fatty acid metabolism-related gene signature for predicting prognosis and immune response in breast cancer
Green synthesized Ag nanoparticles decorated on the surface of Hibiscus tea leaf extract modified reduced graphene oxide: Investigation of its anti-lung carcinoma effects
Shared and distinct biological circuits in effector, memory and exhausted CD8+ T cells revealed by temporal single-cell transcriptomics and epigenetics
LncRNA GAS5 enhances tumor stem cell-like medicated sensitivity of paclitaxel and inhibits epithelial-to-mesenchymal transition by targeting the miR-18a-5p/STK4 pathway in prostate cancer
In vivo CD8+ T cell CRISPR screening reveals control by Fli1 in infection and cancer
DNMT1-induced miR-378a-3p silencing promotes angiogenesis via the NF-κB signaling pathway by targeting TRAF1 in hepatocellular carcinoma
Intratumoral CXCR5+CD8+T associates with favorable clinical outcomes and immunogenic contexture in gastric cancer
DNA primase subunit 1 deteriorated progression of hepatocellular carcinoma by activating AKT/mTOR signaling and UBE2C-mediated P53 ubiquitination
The protocol of a prospective, multicenter, randomized, controlled phase III study evaluating different cycles of oxaliplatin combined with S-1 (SOX) as neoadjuvant chemotherapy for patients with locally advanced gastric cancer: RESONANCE-II trial
TNF-α/TNFR1 regulates the polarization of Kupffer cells to mediate trichloroethylene-induced liver injury
Morbidity and Mortality of Laparoscopic vs Open Total Gastrectomy for Clinical Stage I Gastric Cancer
<i>SNHG16</i> / <i>miR‐605‐3p</i> / <i>TRAF6</i> /NF‐κB feedback loop regulates hepatocellular carcinoma metastasis
HAX-1 promotes the migration and invasion of hepatocellular carcinoma cells through the induction of epithelial–mesenchymal transition via the NF-κB pathway
TRIM13 inhibits cell migration and invasion in clear-cell renal cell carcinoma
High expression of Nectin-4 is associated with unfavorable prognosis in gastric cancer
Overexpression of RCN1 correlates with poor prognosis and progression in non–small cell lung cancer
The expression level and prognostic value of HIPK3 among non-small-cell lung cancer patients in China
Interleukin‑15 suppresses gastric cancer liver metastases by enhancing natural killer cell activity in a murine model
Anatomical variation of infra-pyloric artery origination: A prospective multicenter observational study (IPA-Origin)
CXCR6 predicts poor prognosis in gastric cancer and promotes tumor metastasis through epithelial-mesenchymal transition
Effects of silencing Rab27a gene on biological characteristics and chemosensitivity of non-small cell lung cancer
Investigation of Long Non-coding RNA Expression Profiles in the Substantia Nigra of Parkinson’s Disease
The mTOR/AP-1/VEGF signaling pathway regulates vascular endothelial cell growth