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Rebecca Kristeleit

Guy's and St Thomas' NHS Foundation Trust · GB
Area of research
Reproductive Medicine · Oncology
Research interest
Research interests include Ovarian cancer diagnosis and treatment, PARP inhibition in cancer therapy, Endometrial and Cervical Cancer Treatments, and Histone Deacetylase Inhibitors Research.
h-index
41
citations
8,788
works
349
NIH funding
primary concept
Medicine
email

Recent publications

Pembrolizumab in Patients With Advanced Clear Cell Gynecological Cancer
JAMA Oncology 2025cited by 30position: firstdoi
Hyperinflammatory repolarisation of ovarian cancer patient macrophages by anti-tumour IgE antibody, MOv18, restricts an immunosuppressive macrophage:Treg cell interaction
Nature Communications 2025cited by 13position: middledoi
DDRiver EOC 302: A Randomised Phase 2 Study Of Tuvusertib With Niraparib Or Lartesertib In Patients With Epithelial Ovarian Cancer That Has Progressed On Prior PARP Inhibitor Therapy
International Journal of Gynecological Cancer 2025cited by 3position: firstdoi
BRCA1 secondary splice-site mutations drive exon-skipping and PARP inhibitor resistance
Molecular Cancer 2024cited by 27position: middledoi
Results of a randomised Phase II trial of olaparib, chemotherapy or olaparib and cediranib in patients with platinum-resistant ovarian cancer
British Journal of Cancer 2024cited by 24position: middledoi
PARP inhibition with rucaparib alone followed by combination with atezolizumab: Phase Ib COUPLET clinical study in advanced gynaecological and triple-negative breast cancers
British Journal of Cancer 2024cited by 23position: firstdoi
Safety and anti-tumour activity of the IgE antibody MOv18 in patients with advanced solid tumours expressing folate receptor-alpha: a phase I trial
Nature Communications 2023cited by 35position: middledoi
A Phase 1/2 trial of SRA737 (a Chk1 inhibitor) administered orally in patients with advanced cancer
British Journal of Cancer 2023cited by 34position: firstdoi
Phase I/II sequencing study of azacitidine, epacadostat, and pembrolizumab in advanced solid tumors
British Journal of Cancer 2023cited by 30position: middledoi
Homologous recombination deficiency in newly diagnosed FIGO stage III/IV high-grade epithelial ovarian cancer: a multi-national observational study
International Journal of Gynecological Cancer 2023cited by 17position: middledoi
A Randomized, Phase III Trial to Evaluate Rucaparib Monotherapy as Maintenance Treatment in Patients With Newly Diagnosed Ovarian Cancer (ATHENA–MONO/GOG-3020/ENGOT-ov45)
Journal of Clinical Oncology 2022cited by 372position: lastdoi
Safety and antitumor activity of dostarlimab in patients with advanced or recurrent DNA mismatch repair deficient/microsatellite instability-high (dMMR/MSI-H) or proficient/stable (MMRp/MSS) endometrial cancer: interim results from GARNET—a phase I, single-arm study
Journal for ImmunoTherapy of Cancer 2022cited by 314position: middledoi
Folate receptor alpha in ovarian cancer tissue and patient serum is associated with disease burden and treatment outcomes
British Journal of Cancer 2022cited by 79position: middledoi
A Phase 1B open-label study of gedatolisib (PF-05212384) in combination with other anti-tumour agents for patients with advanced solid tumours and triple-negative breast cancer
British Journal of Cancer 2022cited by 34position: middledoi
Avelumab alone or in combination with chemotherapy versus chemotherapy alone in platinum-resistant or platinum-refractory ovarian cancer (JAVELIN Ovarian 200): an open-label, three-arm, randomised, phase 3 study
The Lancet Oncology 2021cited by 397position: middledoi
Molecular and clinical determinants of response and resistance to rucaparib for recurrent ovarian cancer treatment in ARIEL2 (Parts 1 and 2)
Nature Communications 2021cited by 200position: middledoi
European experts consensus: BRCA/homologous recombination deficiency testing in first-line ovarian cancer
Annals of Oncology 2021cited by 163position: middledoi
ATHENA (GOG-3020/ENGOT-ov45): a randomized, phase III trial to evaluate rucaparib as monotherapy (ATHENA–MONO) and rucaparib in combination with nivolumab (ATHENA–COMBO) as maintenance treatment following frontline platinum-based chemotherapy in ovarian cancer
International Journal of Gynecological Cancer 2021cited by 88position: lastdoi
Lurbinectedin versus pegylated liposomal doxorubicin or topotecan in patients with platinum-resistant ovarian cancer: A multicenter, randomized, controlled, open-label phase 3 study (CORAIL)
Gynecologic Oncology 2021cited by 63position: middledoi
Antitumor activity of dostarlimab in patients with mismatch repair-deficient/microsatellite instability–high tumors: A combined analysis of two cohorts in the GARNET study.
Journal of Clinical Oncology 2021cited by 41position: middledoi
Characterization of patients with long-term responses to rucaparib treatment in recurrent ovarian cancer
Gynecologic Oncology 2021cited by 37position: middledoi
Cost-effectiveness of niraparib, rucaparib, and olaparib for treatment of platinum-resistant, recurrent ovarian carcinoma
Gynecologic Oncology 2020cited by 33position: middledoi
Pharmacokinetics and safety of olaparib in patients with advanced solid tumours and mild or moderate hepatic impairment
British Journal of Clinical Pharmacology 2020cited by 24position: middledoi
A Randomized Phase II Trial of Epigenetic Priming with Guadecitabine and Carboplatin in Platinum-resistant, Recurrent Ovarian Cancer
Clinical Cancer Research 2019cited by 90position: middledoi
Preliminary safety, efficacy, and pharmacokinetic/pharmacodynamic characterization from GARNET, a phase I/II clinical trial of the anti–PD-1 monoclonal antibody, TSR-042, in patients with recurrent or advanced MSI-h and MSS endometrial cancer
Gynecologic Oncology 2019cited by 43position: middledoi
Phase II randomised discontinuation trial of brivanib in patients with advanced solid tumours
European Journal of Cancer 2019cited by 29position: middledoi
Preliminary safety, efficacy, and PK/PD characterization from GARNET, a phase I clinical trial of the anti–PD-1 monoclonal antibody, TSR-042, in patients with recurrent or advanced MSI-H endometrial cancer
Annals of Oncology 2018cited by 23position: middledoi
Antitumor activity and safety of the PARP inhibitor rucaparib in patients with high-grade ovarian carcinoma and a germline or somatic BRCA1 or BRCA2 mutation: Integrated analysis of data from Study 10 and ARIEL2
Gynecologic Oncology 2017cited by 278position: lastdoi
Rucaparib in relapsed, platinum-sensitive high-grade ovarian carcinoma (ARIEL2 Part 1): an international, multicentre, open-label, phase 2 trial
The Lancet Oncology 2016cited by 1,196position: middledoi
PARP inhibitors for BRCA1/2-mutated and sporadic ovarian cancer: current practice and future directions
British Journal of Cancer 2016cited by 209position: lastdoi

Grants

No grants ingested yet.

Frequent collaborators

Ana Oaknin · Universitair Ziekenhuis Leuven9 papers (2015–2024)David M. O’Malley · Bexley Hall6 papers (2015–2022)Amit M. Oza · University Health Network6 papers (2015–2021)Iain A. McNeish · Ovarian Cancer Action5 papers (2015–2024)Robert L. Coleman · MD Anderson Cancer Center Madrid5 papers (2015–2025)Anna V. Tinker · BC Cancer Agency5 papers (2015–2022)Sandra Goble · University of Pittsburgh Medical Center4 papers (2015–2021)Charles A. Leath · St. Vincent's Birmingham4 papers (2018–2022)Bradley J. Monk · University of Cincinnati Medical Center4 papers (2016–2021)Alexandra Léary · Inserm4 papers (2015–2024)Wei Guo · The First Affiliated Hospital, Sun Yat-sen University3 papers (2018–2022)Kevin K. Lin · Saitama Medical University3 papers (2021–2024)Marcia Hall · Hillingdon Hospitals NHS Foundation Trust3 papers (2016–2025)Andrew R. Clamp · Manchester Academic Health Science Centre3 papers (2016–2025)Domenica Lorusso · Pontifícia Universidade Católica de São Paulo3 papers (2016–2021)Gottfried E. Konecny · UCLA Medical Center3 papers (2015–2016)Susana Banerjee · Royal Marsden NHS Foundation Trust3 papers (2021–2024)Lucy Gilbert · McGill University Health Centre3 papers (2018–2022)Isabelle Ray‐Coquard · Université Claude Bernard Lyon 13 papers (2021–2024)Lara Maloney · Clovis Oncology (United States)3 papers (2016–2021)