Area of research
Reproductive Medicine · Endocrinology, Diabetes and Metabolism
Research interest
Research focused on Testosterone (patch) and Endocrinology, with related work in Sex hormone-binding globulin, Gerontology, Prostate cancer. Notable publications include 'European Academy of Andrology (EAA) guidelines on investigation, treatment and monitoring of functional hypogonadism in males', 'Age-associated changes in hypothalamic–pituitary–testicular function in middle-aged and older men are modified by weight change and lifestyle factors: longitudinal results from...', and 'Characteristics of Androgen Deficiency in Late-Onset Hypogonadism: Results from the European Male Aging Study (EMAS)'.
Novel ectopic expression of zona pellucida 3 glycoprotein in lung cancer promotes tumor growth
Association of age, hormonal, and lifestyle factors with the Leydig cell biomarker INSL3 in aging men from the European Male Aging Study cohort
Congenital Hypothyroidism and Hyperthyroidism Alters Adrenal Gene Expression, Development, and Function
Inflammatory markers are associated with quality of life, physical activity, and gait speed but not sarcopenia in aged men (40–79 years)
European Academy of Andrology (EAA) guidelines on investigation, treatment and monitoring of functional hypogonadism in males
Paediatric and adult-onset male hypogonadism
Advances in the Molecular Pathophysiology, Genetics, and Treatment of Primary Ovarian Insufficiency
Genetic Determinants of Circulating Estrogen Levels and Evidence of a Causal Effect of Estradiol on Bone Density in Men
Symptomatic androgen deficiency develops only when both total and free testosterone decline in obese men who may have incident biochemical secondary hypogonadism: Prospective results from the EMAS
Reproductive Hormone Levels Predict Changes in Frailty Status in Community-Dwelling Older Men: European Male Ageing Study Prospective Data
Low Free Testosterone Is Associated with Hypogonadal Signs and Symptoms in Men with Normal Total Testosterone
Sex hormone-binding globulin regulation of androgen bioactivity in vivo: validation of the free hormone hypothesis
Natural history, risk factors and clinical features of primary hypogonadism in ageing men: Longitudinal Data from the European Male Ageing Study
Frailty and bone health in European men
Development of and Recovery from Secondary Hypogonadism in Aging Men: Prospective Results from the EMAS
Associations Between Sex Steroids and the Development of Metabolic Syndrome: A Longitudinal Study in European Men
Chronic widespread pain is associated with worsening frailty in European men
Up-regulation of steroid biosynthesis by retinoid signaling: Implications for aging
Age-associated changes in hypothalamic–pituitary–testicular function in middle-aged and older men are modified by weight change and lifestyle factors: longitudinal results from the European Male Ageing Study
Late-Onset Hypogonadism and Mortality in Aging Men
The ability of three different models of frailty to predict all-cause mortality: Results from the European Male Aging Study (EMAS)
Low Prolactin Is Associated with Sexual Dysfunction and Psychological or Metabolic Disturbances in Middle-Aged and Elderly Men: The European Male Aging Study (EMAS)
Comparisons of Immunoassay and Mass Spectrometry Measurements of Serum Estradiol Levels and Their Influence on Clinical Association Studies in Men
Active Vitamin D (1,25-Dihydroxyvitamin D) and Bone Health in Middle-Aged and Elderly Men: The European Male Aging Study (EMAS)
Characteristics of Androgen Deficiency in Late-Onset Hypogonadism: Results from the European Male Aging Study (EMAS)
Comparison of serum testosterone and estradiol measurements in 3174 European men using platform immunoassay and mass spectrometry; relevance for the diagnostics in aging men
The association of frailty with serum 25-hydroxyvitamin D and parathyroid hormone levels in older European men
Thyroid hormones and male sexual function
Cohort Profile: The European Male Ageing Study