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Laura E. MacConaill

Brigham and Women's Hospital · US
Area of research
Cancer Research · Molecular Biology
Research interest
Research interests include Cancer Genomics and Diagnostics, Epigenetics and DNA Methylation, Bioinformatics and Genomic Networks, and Lung Cancer Treatments and Mutations.
h-index
62
citations
26,852
works
333
NIH funding
primary concept
Medicine
email

Recent publications

Molecular profiling of 888 pediatric tumors informs future precision trials and data-sharing initiatives in pediatric cancer
Nature Communications 2024cited by 7position: middledoi
Comprehensive genomic characterization of HER2-low and HER2-0 breast cancer
Nature Communications 2023cited by 59position: middledoi
Clinical Targeted Next-Generation Panel Sequencing Reveals <i>MYC</i> Amplification Is a Poor Prognostic Factor in Osteosarcoma
JCO Precision Oncology 2023cited by 30position: middledoi
Ancestry-driven recalibration of tumor mutational burden and disparate clinical outcomes in response to immune checkpoint inhibitors
Cancer Cell 2022cited by 115position: middledoi
Molecular profiling identifies targeted therapy opportunities in pediatric solid cancer
Nature Medicine 2022cited by 64position: middledoi
Genomic analysis of early-stage lung cancer reveals a role for TP53 mutations in distant metastasis
Scientific Reports 2022cited by 20position: middledoi
Aligning tumor mutational burden (TMB) quantification across diagnostic platforms: phase II of the Friends of Cancer Research TMB Harmonization Project
Annals of Oncology 2021cited by 179position: middledoi
Tumor Mutational Burden and <i>PTEN</i> Alterations as Molecular Correlates of Response to PD-1/L1 Blockade in Metastatic Triple-Negative Breast Cancer
Clinical Cancer Research 2020cited by 184position: middledoi
Addendum: The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity
Nature 2018cited by 111position: middledoi
Abstract 562: Oncovirus detection and integration analysis from human tumor samples using targeted massively parallel sequencing
Cancer Research 2017cited by 0position: lastdoi
Multicenter Feasibility Study of Tumor Molecular Profiling to Inform Therapeutic Decisions in Advanced Pediatric Solid Tumors
JAMA Oncology 2016cited by 204position: middledoi
Landscape of Genomic Alterations in Pituitary Adenomas
Clinical Cancer Research 2016cited by 131position: middledoi
Whole-exome sequencing and clinical interpretation of formalin-fixed, paraffin-embedded tumor samples to guide precision cancer medicine
Nature Medicine 2014cited by 569position: middledoi
Genomic sequencing of meningiomas identifies oncogenic SMO and AKT1 mutations
Nature Genetics 2013cited by 650position: middledoi
Oncogenic mutations in cervical cancer
Cancer 2013cited by 273position: middledoi
Genomic analysis of diffuse pediatric low-grade gliomas identifies recurrent oncogenic truncating rearrangements in the transcription factor<i>MYBL1</i>
Proceedings of the National Academy of Sciences 2013cited by 223position: middledoi
Mutations in Hedgehog pathway genes in fetal rhabdomyomas
The Journal of Pathology 2013cited by 35position: middledoi
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity
Nature 2012cited by 8,455position: middledoi
Loss of ATRX, Genome Instability, and an Altered DNA Damage Response Are Hallmarks of the Alternative Lengthening of Telomeres Pathway
PLoS Genetics 2012cited by 634position: middledoi
Integrative Genomic Analysis Implicates Gain of <i>PIK3CA</i> at 3q26 and <i>MYC</i> at 8q24 in Chronic Lymphocytic Leukemia
Clinical Cancer Research 2012cited by 81position: middledoi
Germline copy number variation associated with Mendelian inheritance of CLL in two families
Leukemia 2012cited by 11position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Paul Van Hummelen · Natera (United States)4 papers (2013–2017)Megan Hanna · Broad Institute3 papers (2012–2012)William C. Hahn · University of California System3 papers (2012–2013)Nathalie Pochet · Albert Einstein College of Medicine2 papers (2012–2012)Ian F. Dunn · Neurological Surgery2 papers (2013–2016)Mick Correll · Sarah Cannon2 papers (2012–2012)Donna Neuberg · Massachusetts General Hospital2 papers (2012–2012)Aviv Regev · Moscow Institute of Thermal Technology2 papers (2012–2012)Emanuele Palescandolo · Johns Hopkins University2 papers (2013–2013)Stacey M. Fernandes · Harvard University2 papers (2012–2012)Sandro Santagata · Harvard University2 papers (2013–2016)Priscilla K. Brastianos · Harvard University2 papers (2013–2016)Jennifer R. Brown · Harvard University2 papers (2012–2012)Robert T. Jones · MedStar Franklin Square Medical Center2 papers (2013–2013)Matthew D. Ducar · Dana-Farber Cancer Institute2 papers (2013–2017)Lillian Werner · Novartis (United States)2 papers (2012–2012)Neal I. Lindeman · Cornell University2 papers (2016–2020)Peleg Horowitz · University of Illinois Chicago2 papers (2013–2016)Arnold S. Freedman · Harvard University2 papers (2012–2012)Rameen Beroukhim · Broad Institute2 papers (2013–2016)