Area of research
Infectious Diseases · Virology
Research interest
Research interests include HIV Research and Treatment, HIV/AIDS drug development and treatment, HIV/AIDS Research and Interventions, and Immune Cell Function and Interaction.
Enhanced TLR7-dependent production of type I interferon by pDCs underlies pandemic chilblains
The seven enigmas of SARS-CoV-2: From the past to the future
Deleterious variants in the autophagy-related gene RB1CC1/FIP200 impair immunity to SARS-CoV-2
Smoking changes adaptive immunity with persistent effects
SARS-CoV-2 brainstem encephalitis in human inherited DBR1 deficiency
A common form of dominant human IFNAR1 deficiency impairs IFN-α and -ω but not IFN-β-dependent immunity
Heterozygous <i>BTNL8</i> variants in individuals with multisystem inflammatory syndrome in children (MIS-C)
Lack of association between classical HLA genes and asymptomatic SARS-CoV-2 infection
A common NFKB1 variant detected through antibody analysis in UK Biobank predicts risk of infection and allergy
Correction: Rare predicted loss-of-function variants of type I IFN immunity genes are associated with life-threatening COVID-19
Autoantibodies neutralizing type I IFNs underlie West Nile virus encephalitis in ∼40% of patients
Autoantibodies against type I IFNs in humans with alternative NF-κB pathway deficiency
Rare predicted loss-of-function variants of type I IFN immunity genes are associated with life-threatening COVID-19
Humans with inherited MyD88 and IRAK-4 deficiencies are predisposed to hypoxemic COVID-19 pneumonia
Back-to-Africa introductions of Mycobacterium tuberculosis as the main cause of tuberculosis in Dar es Salaam, Tanzania
Africa-specific human genetic variation near CHD1L associates with HIV-1 load
Human Genomics of COVID-19 Pneumonia: Contributions of Rare and Common Variants
Associations of genetic and infectious risk factors with coronary heart disease
Additional file 2 of Rare predicted loss-of-function variants of type I IFN immunity genes are associated with life-threatening COVID-19
Human genetic and immunological determinants of critical COVID-19 pneumonia
Studying severe long COVID to understand post-infectious disorders beyond COVID-19
Autoantibodies against type I IFNs in patients with critical influenza pneumonia
Recessive inborn errors of type I IFN immunity in children with COVID-19 pneumonia
The immune factors driving DNA methylation variation in human blood
A highly virulent variant of HIV-1 circulating in the Netherlands
Respiratory viral infections in otherwise healthy humans with inherited IRF7 deficiency
The combined impact of persistent infections and human genetic variation on C-reactive protein levels
Decoding the Human Genetic and Immunological Basis of COVID-19 mRNA Vaccine-Induced Myocarditis
The combined impact of persistent infections and human genetic variation on C-reactive protein levels
Associations of genetic and infectious risk factors with coronary heart disease