Area of research
Molecular Biology · Aging
Research interest
Research interests include Bioinformatics and Genomic Networks, Genetics, Aging, and Longevity in Model Organisms, Reproductive Biology and Fertility, and Pluripotent Stem Cells Research.
A platform for the biomedical application of large language models
Innovations in aging biology: highlights from the ARDD emerging science & technologies workshop
Validation of biomarkers of aging
Biomarkers of aging for the identification and evaluation of longevity interventions
A conserved long-distance telomeric silencing mechanism suppresses mTOR signaling in aging human fibroblasts
Molecular Characterization of the Response to Conventional Chemotherapeutics in Pro-B-ALL Cell Lines in Terms of Tumor Relapse
Ranking Biomarkers of Aging by Citation Profiling and Effort Scoring
Health and longevity studies in C. elegans: the “healthy worm database” reveals strengths, weaknesses and gaps of test compound-based studies
Genes implicated in <i>Caenorhabditis elegans</i> and human health regulate stress resistance and physical abilities in aged <i>Caenorhabditis elegans</i>
The preventive strategy for pandemics in the elderly is to collect in advance samples & data to counteract chronic inflammation (inflammaging)
Healthspan pathway maps in C. elegans and humans highlight transcription, proliferation/biosynthesis and lipids
Combination of the PI3K inhibitor Idelalisib with the conventional cytostatics cytarabine and dexamethasone leads to changes in pathway activation that induce anti-proliferative effects in B lymphoblastic leukaemia cell lines
Combined Casein Kinase II inhibition and epigenetic modulation in acute B-lymphoblastic leukemia
Unraveling the Heterogeneous Mutational Signature of Spontaneously Developing Tumors in MLH1−/− Mice
Unraveling the heterogeneous mutational signature of spontaneously developing tumors in MLH1 <sup>-/-</sup> mice
Health and Aging: Unifying Concepts, Scores, Biomarkers and Pathways
FocusHeuristics – expression-data-driven network optimization and disease gene prediction
Ageing with elegans: a research proposal to map healthspan pathways
<i>In Silico</i> Approaches and the Role of Ontologies in Aging Research